General information
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| PDB ID | 5V05 |
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| Title | CRYSTAL STRUCTURE OF HUMAN EXONUCLEASE 1 EXO1 (WT) IN COMPLEX WITH 5' RECESSED-END DNA (RIII) | ||||
| PDB header | HYDROLASE/DNA | ||||
| Date | 2017-02-28 | ||||
| Experimental method | X-RAY DIFFRACTION | ||||
| Resolution (A) | 2.9 | ||||
| Kind | dna | ||||
| Organism | HOMO SAPIENS, SYNTHETIC CONSTRUCT | ||||
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Quick Links
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Composition of PDB entry and biounits
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| File: | Protein chains: | DNA chains: | RNA chains: | No. of models: | Action: |
| PDB entry: | |||||
| pdb5v05.pdb | Z | AB | 0 |
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| Biounits: | |||||
| 5v05.pdb1.pdb | Z | AB | 1 |
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Pfam domains
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| Name: | Type: | Domain: | E-value: | Significance: | Clan: | Prot. chain: | Start res.: | End res.: | Nuc. chains: | Int. mode: | Action: |
XPG_I
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Family | Q9UQ84_141-225 | 2.7e-23 | 1 |
CL0464
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Z | 141 | 225 |
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XPG_N
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Family | Q9UQ84_2-99 | 4e-21 | 1 |
CL0280
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Z | 2 | 99 | AB | H-Bb H-Mj H-Mn |
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SCOP domains
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| No SCOP domains | |||||||
| GO terms | ||
| Protein chains: | GO type: | GO description: |
| Z=1-352 | C | nuclear body |
| Z=1-352 | C | nucleoplasm |
| Z=1-352 | C | nucleus |
| Z=1-352 | C | plasma membrane |
| Z=1-352 | F | 5'-3' exodeoxyribonuclease activity |
| Z=1-352 | F | 5'-3' exonuclease activity |
| Z=1-352 | F | 5'-flap endonuclease activity |
| Z=1-352 | F | chromatin binding |
| Z=1-352 | F | DNA binding |
| Z=1-352 | F | double-stranded DNA 5'-3' exodeoxyribonuclease activity |
| Z=1-352 | F | exonuclease activity |
| Z=1-352 | F | flap endonuclease activity |
| Z=1-352 | F | metal ion binding |
| Z=1-352 | F | RNA-DNA hybrid ribonuclease activity |
| Z=1-352 | F | single-stranded DNA 5'-3' exodeoxyribonuclease activity |
| Z=1-352 | P | DNA recombination |
| Z=1-352 | P | DNA repair |
| Z=1-352 | P | DNA replication |
| Z=1-352 | P | humoral immune response mediated by circulating immunoglobulin |
| Z=1-352 | P | isotype switching |
| Z=1-352 | P | meiotic cell cycle |
| Z=1-352 | P | mismatch repair |
| Z=1-352 | P | regulation of signal transduction by p53 class mediator |
| Z=1-352 | P | somatic hypermutation of immunoglobulin genes |
| Z=1-352 | P | t-circle formation |
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Sequences
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Download file with secondary structure created by Stride
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5v05.pdb1.pdb:
[
download sequences in FASTA format
]
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A (dna):
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B (dna):
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Z (protein):
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