General information
PDB ID 6AKP
Title CRYSTAL STRUCTURAL OF FOXC2 DNA BINDING DOMAIN BOUND TO PC PROMOTER
PDB header DNA BINDING PROTEIN/DNA
Date 2018-09-03
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.32
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6akp.pdb C AB 0
Biounits:
6akp.pdb1.pdb C AB 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Forkhead Domain Q99958_72-157 7.4e-39 1 CL0123 C 71 157 B  H-Bb H-Mj S-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
C=72-172 C nuclear body
C=72-172 C nuclear chromatin
C=72-172 C nucleoplasm
C=72-172 C nucleus
C=72-172 F chromatin DNA binding
C=72-172 F DNA-binding transcription activator activity
C=72-172 F DNA-binding transcription activator activity, RNA polymerase II-specific
C=72-172 F DNA-binding transcription factor activity, RNA polymerase II-specific
C=72-172 F identical protein binding
C=72-172 F promoter-specific chromatin binding
C=72-172 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
C=72-172 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
C=72-172 F sequence-specific DNA binding
C=72-172 F sequence-specific double-stranded DNA binding
C=72-172 F transcription regulatory region sequence-specific DNA binding
C=72-172 P anatomical structure morphogenesis
C=72-172 P artery morphogenesis
C=72-172 P blood vessel remodeling
C=72-172 P branching involved in blood vessel morphogenesis
C=72-172 P camera-type eye development
C=72-172 P cardiac muscle cell proliferation
C=72-172 P cell differentiation
C=72-172 P collagen fibril organization
C=72-172 P embryonic heart tube development
C=72-172 P embryonic viscerocranium morphogenesis
C=72-172 P glomerular endothelium development
C=72-172 P glomerular mesangial cell development
C=72-172 P glomerular visceral epithelial cell differentiation
C=72-172 P heart development
C=72-172 P insulin receptor signaling pathway
C=72-172 P lymphangiogenesis
C=72-172 P mesoderm development
C=72-172 P metanephros development
C=72-172 P negative regulation of apoptotic process involved in outflow tract morphogenesis
C=72-172 P negative regulation of cold-induced thermogenesis
C=72-172 P negative regulation of transcription by RNA polymerase II
C=72-172 P neural crest cell development
C=72-172 P Notch signaling pathway
C=72-172 P ossification
C=72-172 P paraxial mesodermal cell fate commitment
C=72-172 P positive regulation of cell adhesion mediated by integrin
C=72-172 P positive regulation of cell migration involved in sprouting angiogenesis
C=72-172 P positive regulation of endothelial cell migration
C=72-172 P positive regulation of transcription by RNA polymerase II
C=72-172 P positive regulation of transcription, DNA-templated
C=72-172 P positive regulation of vascular wound healing
C=72-172 P regulation of blood vessel diameter
C=72-172 P regulation of organ growth
C=72-172 P regulation of transcription by RNA polymerase II
C=72-172 P response to hormone
C=72-172 P somitogenesis
C=72-172 P ureteric bud development
C=72-172 P vascular endothelial growth factor receptor signaling pathway
C=72-172 P ventricular cardiac muscle tissue morphogenesis
Sequences
Download file with secondary structure created by Stride  
6akp.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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C (protein): 
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