General information
PDB ID 6AS7
Title CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN DNA-PRIMED DNA TEMPLATE AND DCTP
PDB header REPLICATION/DNA
Date 2017-08-23
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.95
Kind dna
Organism HOMO SAPIENS, UNIDENTIFIED
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6as7.pdb A BC 0
Biounits:
6as7.pdb1.pdb A BC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
DNA_pol_B Family P09884_774-1227 1e-129 1 CL0194 A 774 1227 BC  H-Bb L-Bb L-Mj L-Mn 
DNA_pol_B_exo1 Family P09884_369-711 8.8e-61 1 CL0219 A 369 711   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=336-1257 C alpha DNA polymerase:primase complex
A=336-1257 C cytosol
A=336-1257 C nuclear envelope
A=336-1257 C nuclear matrix
A=336-1257 C nucleolus
A=336-1257 C nucleoplasm
A=336-1257 C nucleus
A=336-1257 F 4 iron, 4 sulfur cluster binding
A=336-1257 F chromatin binding
A=336-1257 F DNA binding
A=336-1257 F DNA replication origin binding
A=336-1257 F DNA-directed DNA polymerase activity
A=336-1257 F metal ion binding
A=336-1257 F nucleotide binding
A=336-1257 F protein kinase binding
A=336-1257 F purine nucleotide binding
A=336-1257 F pyrimidine nucleotide binding
A=336-1257 F single-stranded DNA binding
A=336-1257 P DNA repair
A=336-1257 P DNA replication
A=336-1257 P DNA replication initiation
A=336-1257 P DNA replication, synthesis of RNA primer
A=336-1257 P DNA strand elongation involved in DNA replication
A=336-1257 P DNA synthesis involved in DNA repair
A=336-1257 P double-strand break repair via nonhomologous end joining
A=336-1257 P G1/S transition of mitotic cell cycle
A=336-1257 P lagging strand elongation
A=336-1257 P leading strand elongation
A=336-1257 P mitotic DNA replication initiation
A=336-1257 P regulation of transcription involved in G1/S transition of mitotic cell cycle
A=336-1257 P regulation of type I interferon production
A=336-1257 P telomere maintenance via semi-conservative replication
A=336-1257 P viral process
Sequences
Download file with secondary structure created by Stride  
6as7.pdb1.pdb:   [ download sequences in FASTA format ]
B (dna): 
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C (dna): 
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A (protein): 
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