General information
PDB ID 6CNP
Title CRYSTAL STRUCTURE OF MBD2 COMPLEX WITH METHYLATED CPG ISLAND
PDB header TRANSCRIPTION/DNA
Date 2018-03-08
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.1
Kind dna
Organism HOMO SAPIENS, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6cnp.pdb AB CDEF 0
Biounits:
6cnp.pdb1.pdb A CD 1
6cnp.pdb2.pdb B EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MBD Domain Q9UBB5_148-215 2.2e-24 1 CL0081 A 148 215 CD  H-Bb S-Bb S-Mj L-Bb L-Mj 
MBD Domain Q9UBB5_153-210 2.9e-21 1 CL0081 B 153 210 EF  H-Bb S-Bb S-Mj L-Bb L-Mj 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B=143-220 C cytosol
A/B=143-220 C heterochromatin
A/B=143-220 C histone deacetylase complex
A/B=143-220 C host cell nucleus
A/B=143-220 C nuclear chromatin
A/B=143-220 C nucleoplasm
A/B=143-220 C nucleus
A/B=143-220 C protein-containing complex
A/B=143-220 F C2H2 zinc finger domain binding
A/B=143-220 F chromatin binding
A/B=143-220 F methyl-CpG binding
A/B=143-220 F mRNA binding
A/B=143-220 F protein domain specific binding
A/B=143-220 F satellite DNA binding
A/B=143-220 F siRNA binding
A/B=143-220 P aging
A/B=143-220 P ATP-dependent chromatin remodeling
A/B=143-220 P cellular protein-containing complex assembly
A/B=143-220 P cellular response to organic cyclic compound
A/B=143-220 P DNA methylation-dependent heterochromatin assembly
A/B=143-220 P embryonic organ development
A/B=143-220 P heart development
A/B=143-220 P maternal behavior
A/B=143-220 P negative regulation of transcription by RNA polymerase II
A/B=143-220 P negative regulation of transcription, DNA-templated
A/B=143-220 P positive regulation of chromatin binding
A/B=143-220 P positive regulation of Wnt signaling pathway
A/B=143-220 P rDNA heterochromatin assembly
A/B=143-220 P regulation of cell population proliferation
A/B=143-220 P regulation of DNA methylation
A/B=143-220 P response to estradiol
A/B=143-220 P response to mechanical stimulus
A/B=143-220 P response to nutrient levels
Sequences
Download file with secondary structure created by Stride  
6cnp.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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6cnp.pdb2.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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B (protein): 
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