General information
PDB ID 6DKS
Title STRUCTURE OF THE RBPJ-SHARP-DNA REPRESSOR COMPLEX
PDB header TRANSCRIPTION/DNA
Date 2018-05-30
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.78
Kind dna
Organism MUS MUSCULUS, ESCHERICHIA COLI O157:H7
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6dks.pdb CDGH ABEF 0
Biounits:
6dks.pdb1.pdb CDGH ABEF 1
6dks.pdb2.pdb CD AB 1
6dks.pdb3.pdb GH EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
BTD Domain P31266_232-354 5.7e-60 1 CL0066 C 232 354   
BTD Domain P31266_232-354 5.7e-60 1 CL0066 C 232 354   
BTD Domain P31266_232-354 5.7e-60 1 CL0066 C 232 354   
BTD Domain P31266_232-354 5.7e-60 1 CL0066 C 232 354   
LAG1-DNAbind Domain P31266_74-204 1.2e-43 1 CL0073 C 74 204 AB  L-Bb L-Mj 
LAG1-DNAbind Domain P31266_74-204 1.2e-43 1 CL0073 C 74 204 AB  L-Bb L-Mj 
LAG1-DNAbind Domain P31266_74-204 1.2e-43 1 CL0073 C 74 204 AB  L-Bb L-Mj 
LAG1-DNAbind Domain P31266_74-204 1.2e-43 1 CL0073 C 74 204 AB  L-Bb L-Mj 
TIG_SUH Domain P31266_380-470 5.2e-32 1 CL0159 C 380 470   
TIG_SUH Domain P31266_380-470 5.2e-32 1 CL0159 C 380 470   
TIG_SUH Domain P31266_380-470 5.2e-32 1 CL0159 C 380 470   
TIG_SUH Domain P31266_380-470 5.2e-32 1 CL0159 C 380 470   
BTD Domain P31266_232-354 6.3e-62 1 CL0066 G 232 354   
BTD Domain P31266_232-354 6.3e-62 1 CL0066 G 232 354   
BTD Domain P31266_232-354 6.3e-62 1 CL0066 G 232 354   
BTD Domain P31266_232-354 6.3e-62 1 CL0066 G 232 354   
LAG1-DNAbind Domain P31266_74-204 3.4e-47 1 CL0073 G 74 204 EF  L-Bb L-Mj 
LAG1-DNAbind Domain P31266_74-204 3.4e-47 1 CL0073 G 74 204 EF  L-Bb L-Mj 
LAG1-DNAbind Domain P31266_74-204 3.4e-47 1 CL0073 G 74 204 EF  L-Bb L-Mj 
LAG1-DNAbind Domain P31266_74-204 3.4e-47 1 CL0073 G 74 204 EF  L-Bb L-Mj 
TIG_SUH Domain P31266_380-470 5.3e-32 1 CL0159 G 380 470   
TIG_SUH Domain P31266_380-470 5.3e-32 1 CL0159 G 380 470   
TIG_SUH Domain P31266_380-470 5.3e-32 1 CL0159 G 380 470   
TIG_SUH Domain P31266_380-470 5.3e-32 1 CL0159 G 380 470   
SBP_bac_1 Family P0AEY0_37-317 2.6e-42 1 CL0177 D 12 291   
SBP_bac_1 Family P0AEY0_37-317 2.6e-42 1 CL0177 D 12 291   
SBP_bac_1 Family P0AEY0_37-317 2.6e-42 1 CL0177 D 12 291   
SBP_bac_1 Family P0AEY0_37-317 2.6e-42 1 CL0177 D 12 291   
SBP_bac_1 Family P0AEY0_37-317 2.6e-42 1 CL0177 H 12 291   
SBP_bac_1 Family P0AEY0_37-317 2.6e-42 1 CL0177 H 12 291   
SBP_bac_1 Family P0AEY0_37-317 2.6e-42 1 CL0177 H 12 291   
SBP_bac_1 Family P0AEY0_37-317 2.6e-42 1 CL0177 H 12 291   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
C/G=53-474 C cytoplasm
C/G=53-474 C MAML1-RBP-Jkappa- ICN1 complex
C/G=53-474 C nucleolus
C/G=53-474 C nucleoplasm
C/G=53-474 C nucleus
C/G=53-474 C protein-containing complex
C/G=53-474 C protein-DNA complex
C/G=53-474 C transcription regulator complex
C/G=53-474 C transcription repressor complex
C/G=53-474 F chromatin binding
C/G=53-474 F DNA binding
C/G=53-474 F DNA-binding transcription activator activity, RNA polymerase II-specific
C/G=53-474 F protein N-terminus binding
C/G=53-474 F protein-containing complex binding
C/G=53-474 F repressing transcription factor binding
C/G=53-474 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
C/G=53-474 F RNA polymerase II repressing transcription factor binding
C/G=53-474 F sequence-specific DNA binding
C/G=53-474 F transcription factor binding
C/G=53-474 P angiogenesis
C/G=53-474 P aortic valve development
C/G=53-474 P arterial endothelial cell fate commitment
C/G=53-474 P artery morphogenesis
C/G=53-474 P atrioventricular canal development
C/G=53-474 P auditory receptor cell fate commitment
C/G=53-474 P B cell differentiation
C/G=53-474 P blood vessel endothelial cell fate specification
C/G=53-474 P blood vessel lumenization
C/G=53-474 P blood vessel remodeling
C/G=53-474 P cardiac left ventricle morphogenesis
C/G=53-474 P cell fate commitment
C/G=53-474 P club cell differentiation
C/G=53-474 P defense response to bacterium
C/G=53-474 P determination of heart left/right asymmetry
C/G=53-474 P dorsal aorta morphogenesis
C/G=53-474 P endocardium development
C/G=53-474 P endocardium morphogenesis
C/G=53-474 P epidermal cell fate specification
C/G=53-474 P epithelial to mesenchymal transition
C/G=53-474 P epithelial to mesenchymal transition involved in endocardial cushion formation
C/G=53-474 P hair follicle maturation
C/G=53-474 P heart development
C/G=53-474 P heart looping
C/G=53-474 P hemopoiesis
C/G=53-474 P humoral immune response
C/G=53-474 P inflammatory response to antigenic stimulus
C/G=53-474 P interleukin-4 production
C/G=53-474 P keratinocyte differentiation
C/G=53-474 P labyrinthine layer blood vessel development
C/G=53-474 P myeloid dendritic cell differentiation
C/G=53-474 P negative regulation of cell differentiation
C/G=53-474 P negative regulation of cell population proliferation
C/G=53-474 P negative regulation of cold-induced thermogenesis
C/G=53-474 P negative regulation of neuron projection development
C/G=53-474 P negative regulation of ossification
C/G=53-474 P negative regulation of smooth muscle cell apoptotic process
C/G=53-474 P negative regulation of smooth muscle cell migration
C/G=53-474 P negative regulation of transcription by RNA polymerase II
C/G=53-474 P negative regulation of transcription, DNA-templated
C/G=53-474 P neuron differentiation
C/G=53-474 P Notch signaling pathway
C/G=53-474 P Notch signaling pathway involved in arterial endothelial cell fate commitment
C/G=53-474 P outflow tract morphogenesis
C/G=53-474 P pituitary gland development
C/G=53-474 P positive regulation of BMP signaling pathway
C/G=53-474 P positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
C/G=53-474 P positive regulation of cardiac muscle cell proliferation
C/G=53-474 P positive regulation of cell population proliferation
C/G=53-474 P positive regulation of cell proliferation involved in heart morphogenesis
C/G=53-474 P positive regulation of ephrin receptor signaling pathway
C/G=53-474 P positive regulation of ERBB signaling pathway
C/G=53-474 P positive regulation of gene expression
C/G=53-474 P positive regulation of Notch signaling pathway involved in heart induction
C/G=53-474 P positive regulation of smooth muscle cell proliferation
C/G=53-474 P positive regulation of transcription by RNA polymerase II
C/G=53-474 P positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
C/G=53-474 P positive regulation of transcription of Notch receptor target
C/G=53-474 P positive regulation of transcription, DNA-templated
C/G=53-474 P pulmonary valve development
C/G=53-474 P regulation of cell adhesion involved in heart morphogenesis
C/G=53-474 P regulation of cell population proliferation
C/G=53-474 P regulation of gene expression
C/G=53-474 P regulation of timing of cell differentiation
C/G=53-474 P regulation of transcription by RNA polymerase II
C/G=53-474 P regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
C/G=53-474 P sebaceous gland development
C/G=53-474 P secondary heart field specification
C/G=53-474 P somatic stem cell population maintenance
C/G=53-474 P somitogenesis
C/G=53-474 P ventricular septum morphogenesis
C/G=53-474 P ventricular trabecula myocardium morphogenesis
Sequences
Download file with secondary structure created by Stride  
6dks.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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E (dna): 
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F (dna): 
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C (protein): 
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D (protein): 
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G (protein): 
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H (protein): 
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6dks.pdb2.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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C (protein): 
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D (protein): 
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6dks.pdb3.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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G (protein): 
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H (protein): 
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