General information
PDB ID 6L6L
Title STRUCTURAL BASIS OF NR4A2 HOMODIMERS BINDING TO SELECTIVE NUR- RESPONSIVE ELEMENTS
PDB header DNA BINDING PROTEIN
Date 2019-10-29
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.78
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6l6l.pdb AB CD 0
Biounits:
6l6l.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-C4 Domain P43354_262-330 1.2e-32 1 CL0167 A 262 330 CD  H-Bb H-Mj S-Bb S-Mj L-Bb L-Mj 
zf-C4 Domain P43354_262-330 1.1e-32 1 CL0167 B 262 330 CD  H-Bb H-Mj S-Bb S-Mj L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B=262-346 C cytoplasm
A/B=262-346 C nuclear chromatin
A/B=262-346 C nuclear speck
A/B=262-346 C nucleoplasm
A/B=262-346 C nucleus
A/B=262-346 C protein-containing complex
A/B=262-346 C transcription regulator complex
A/B=262-346 F beta-catenin binding
A/B=262-346 F DNA binding
A/B=262-346 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=262-346 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=262-346 F glucocorticoid receptor binding
A/B=262-346 F nuclear receptor activity
A/B=262-346 F protein heterodimerization activity
A/B=262-346 F retinoid X receptor binding
A/B=262-346 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=262-346 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/B=262-346 F sequence-specific DNA binding
A/B=262-346 F sequence-specific double-stranded DNA binding
A/B=262-346 F zinc ion binding
A/B=262-346 P adult locomotory behavior
A/B=262-346 P canonical Wnt signaling pathway
A/B=262-346 P cellular response to corticotropin-releasing hormone stimulus
A/B=262-346 P cellular response to extracellular stimulus
A/B=262-346 P cellular response to oxidative stress
A/B=262-346 P central nervous system neuron differentiation
A/B=262-346 P central nervous system projection neuron axonogenesis
A/B=262-346 P dopamine biosynthetic process
A/B=262-346 P dopaminergic neuron differentiation
A/B=262-346 P fat cell differentiation
A/B=262-346 P general adaptation syndrome
A/B=262-346 P habenula development
A/B=262-346 P midbrain dopaminergic neuron differentiation
A/B=262-346 P negative regulation of apoptotic signaling pathway
A/B=262-346 P negative regulation of neuron apoptotic process
A/B=262-346 P negative regulation of transcription by RNA polymerase II
A/B=262-346 P neuron maturation
A/B=262-346 P neuron migration
A/B=262-346 P positive regulation of catalytic activity
A/B=262-346 P positive regulation of transcription by RNA polymerase II
A/B=262-346 P post-embryonic development
A/B=262-346 P regulation of dopamine metabolic process
A/B=262-346 P regulation of respiratory gaseous exchange
A/B=262-346 P response to amphetamine
A/B=262-346 P response to hypoxia
A/B=262-346 P signal transduction
A/B=262-346 P transcription initiation from RNA polymerase II promoter
A/B=262-346 P transcription, DNA-templated
Sequences
Download file with secondary structure created by Stride  
6l6l.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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