General information
PDB ID 6LC1
Title STRUCTURAL BASIS OF NR4A1 BOUND TO THE HUMAN PITUITARY PROOPIOMELANOCORTIN GENE PROMOTER
PDB header DNA BINDING PROTEIN/DNA
Date 2019-11-16
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.12
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6lc1.pdb JADG ILCF 0
Biounits:
6lc1.pdb1.pdb JG IL 1
6lc1.pdb2.pdb AD CF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-C4 Domain P22736_266-334 2.7e-32 1 CL0167 A 266 334 CF  H-Bb H-Mj S-Bb S-Mj L-Bb 
zf-C4 Domain P22736_266-334 1.7e-32 1 CL0167 D 265 334 CF  H-Bb H-Mj S-Bb S-Mj L-Bb 
zf-C4 Domain P22736_266-334 2.7e-32 1 CL0167 G 266 334 IL  H-Bb H-Mj S-Bb S-Mj L-Bb 
zf-C4 Domain P22736_266-334 1.7e-32 1 CL0167 J 265 334 IL  H-Bb H-Mj S-Bb S-Mj L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/D/G/J=265-351 C cytosol
A/D/G/J=265-351 C mitochondrion
A/D/G/J=265-351 C nuclear chromatin
A/D/G/J=265-351 C nuclear membrane
A/D/G/J=265-351 C nucleoplasm
A/D/G/J=265-351 C nucleus
A/D/G/J=265-351 C transcription regulator complex
A/D/G/J=265-351 F DNA binding
A/D/G/J=265-351 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/D/G/J=265-351 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/D/G/J=265-351 F glucocorticoid receptor binding
A/D/G/J=265-351 F nuclear receptor activity
A/D/G/J=265-351 F protein heterodimerization activity
A/D/G/J=265-351 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/D/G/J=265-351 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/D/G/J=265-351 F sequence-specific DNA binding
A/D/G/J=265-351 F sequence-specific double-stranded DNA binding
A/D/G/J=265-351 F zinc ion binding
A/D/G/J=265-351 P cell migration involved in sprouting angiogenesis
A/D/G/J=265-351 P cellular response to corticotropin-releasing hormone stimulus
A/D/G/J=265-351 P cellular response to fibroblast growth factor stimulus
A/D/G/J=265-351 P cellular response to vascular endothelial growth factor stimulus
A/D/G/J=265-351 P endothelial cell chemotaxis
A/D/G/J=265-351 P fat cell differentiation
A/D/G/J=265-351 P negative regulation of cell cycle
A/D/G/J=265-351 P positive regulation of endothelial cell proliferation
A/D/G/J=265-351 P positive regulation of transcription by RNA polymerase II
A/D/G/J=265-351 P regulation of type B pancreatic cell proliferation
A/D/G/J=265-351 P signal transduction
A/D/G/J=265-351 P transcription initiation from RNA polymerase II promoter
Sequences
Download file with secondary structure created by Stride  
6lc1.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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L (dna): 
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G (protein): 
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J (protein): 
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6lc1.pdb2.pdb:   [ download sequences in FASTA format ]
C (dna): 
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F (dna): 
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A (protein): 
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D (protein): 
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