General information
PDB ID 6NJ9
Title ACTIVE STATE DOT1L BOUND TO THE H2B-UBIQUITINATED NUCLEOSOME, 2-TO-1 COMPLEX
PDB header STRUCTURAL PROTEIN/TRANSFERASE/DNA
Date 2019-01-02
Experimental method ELECTRON MICROSCOPY
Resolution (A) 2.96
Kind dna
Organism XENOPUS LAEVIS, SYNTHETIC CONSTRUCT, HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6nj9.pdb ABCDEFGHKLMN IJ 0
Biounits:
6nj9.pdb1.pdb ABCDEFGHKLMN IJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain P84233_37-132 8.8e-38 1 CL0012 A 37 131 IJ  H-Bb H-Mj L-Bb L-Mn 
CENP-T_C Domain P62799_18-99 5.3e-08 1 CL0012 B 19 98 IJ  H-Bb L-Bb 
Histone Domain P06897_13-91 5.1e-16 1 CL0012 C 11 90 IJ  H-Bb S-Bb L-Bb 
Histone Domain P02281_33-102 4.2e-22 1 CL0012 D 30 101 IJ  H-Bb S-Bb L-Bb 
Histone Domain P84233_37-132 8.8e-38 1 CL0012 E 37 131 IJ  H-Bb H-Mj L-Bb L-Mn 
CENP-T_C Domain P62799_18-99 5.3e-08 1 CL0012 F 19 98 IJ  H-Bb L-Bb 
Histone Domain P06897_13-91 5.1e-16 1 CL0012 G 11 90 IJ  H-Bb S-Bb L-Bb 
Histone Domain P02281_33-102 4.2e-22 1 CL0012 H 30 101 IJ  H-Bb S-Bb L-Bb 
DOT1 Domain Q8TEK3_115-317 9.1e-84 1 CL0063 K 115 317   
ubiquitin Domain J3QS39_3-74 5.2e-35 1 CL0072 L 3 74   
DOT1 Domain 9.1e-84 1 CL0063 M 115 317
ubiquitin Domain 5.2e-35 1 CL0072 N 3 74
Histone_H2A_C Family P06897_92-120 4.2e-18 1 No_clan C 91 119   
Histone_H2A_C Family P06897_92-120 4.2e-18 1 No_clan G 91 119   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/E=2-136 C nucleoplasm
A/E=2-136 C nucleosome
A/E=2-136 F DNA binding
A/E=2-136 F protein heterodimerization activity
B/F=2-103 C host cell nucleus
B/F=2-103 C nucleosome
B/F=2-103 C nucleus
B/F=2-103 F DNA binding
B/F=2-103 F protein heterodimerization activity
B/F=2-103 P DNA-templated transcription, initiation
C/G=2-130 C nucleosome
C/G=2-130 C nucleus
C/G=2-130 F DNA binding
C/G=2-130 F protein heterodimerization activity
D/H=5-126 C nucleosome
D/H=5-126 C nucleus
D/H=5-126 F DNA binding
D/H=5-126 F protein heterodimerization activity
K=2-416 C chromosome, telomeric region
K=2-416 C intracellular membrane-bounded organelle
K=2-416 C nucleoplasm
K=2-416 C nucleus
K=2-416 C protein-containing complex
K=2-416 F DNA binding
K=2-416 F histone methyltransferase activity
K=2-416 F histone methyltransferase activity (H3-K79 specific)
K=2-416 F histone-lysine N-methyltransferase activity
K=2-416 F transcription factor binding
K=2-416 P chromatin silencing at telomere
K=2-416 P DNA damage checkpoint
K=2-416 P DNA repair
K=2-416 P histone H3-K79 methylation
K=2-416 P positive regulation of cell population proliferation
K=2-416 P positive regulation of transcription by RNA polymerase II
K=2-416 P regulation of receptor signaling pathway via JAK-STAT
K=2-416 P regulation of transcription regulatory region DNA binding
K=2-416 P telomere organization
Sequences
Download file with secondary structure created by Stride  
6nj9.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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H (protein): 
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K (protein): 
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L (protein): 
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M (protein): 
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N (protein): 
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