General information
PDB ID 6PUW
Title STRUCTURE OF HIV CLEAVED SYNAPTIC COMPLEX (CSC) INTASOME BOUND WITH MAGNESIUM AND BICTEGRAVIR (BIC)
PDB header VIRAL PROTEIN/DNA
Date 2019-07-18
Experimental method ELECTRON MICROSCOPY
Resolution (A) 2.9
Kind dna
Organism HUMAN IMMUNODEFICIENCY VIRUS 1
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6puw.pdb ABCD EF 0
Biounits:
6puw.pdb1.pdb ABCD EF 2
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Integrase_Zn Domain P12497_1155-1192 2.9e-16 1 No_clan A 8 45   
rve Domain P12497_1202-1292 1.4e-13 1 CL0219 A 54 145 EF  L-Bb 
IN_DBD_C Domain P12497_1372-1415 0.00078 0 CL0010 A 220 268   
Integrase_Zn Domain P12497_1155-1192 1.9e-16 1 No_clan B 8 57   
rve Domain P12497_1204-1286 2.6e-11 1 CL0219 B 43 153   
IN_DBD_C Domain P12497_1372-1406 0.00029 0 CL0010 B 239 259   
IN_DBD_C Domain P12497_1372-1415 2.7e-20 1 CL0010 C 225 268 E  S-Bb 
IN_DBD_C Domain P12497_1372-1415 9.2e-21 1 CL0010 D 225 268 EF  S-Bb L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B/C/D=1-64 C cytoplasm
A/B/C/D=1-64 F DNA binding
A/B/C/D=1-64 F endoribonuclease activity
A/B/C/D=1148-1435 C host cell nucleus
A/B/C/D=1148-1435 C host cell plasma membrane
A/B/C/D=1148-1435 C host multivesicular body
A/B/C/D=1148-1435 C viral nucleocapsid
A/B/C/D=1148-1435 C virion membrane
A/B/C/D=1148-1435 F aspartic-type endopeptidase activity
A/B/C/D=1148-1435 F DNA binding
A/B/C/D=1148-1435 F DNA-directed DNA polymerase activity
A/B/C/D=1148-1435 F exoribonuclease H activity
A/B/C/D=1148-1435 F identical protein binding
A/B/C/D=1148-1435 F lipid binding
A/B/C/D=1148-1435 F phosphatidylinositol-4,5-bisphosphate binding
A/B/C/D=1148-1435 F RNA binding
A/B/C/D=1148-1435 F RNA-directed DNA polymerase activity
A/B/C/D=1148-1435 F RNA-DNA hybrid ribonuclease activity
A/B/C/D=1148-1435 F structural molecule activity
A/B/C/D=1148-1435 F zinc ion binding
A/B/C/D=1148-1435 P DNA integration
A/B/C/D=1148-1435 P DNA recombination
A/B/C/D=1148-1435 P establishment of integrated proviral latency
A/B/C/D=1148-1435 P induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
A/B/C/D=1148-1435 P suppression by virus of host gene expression
A/B/C/D=1148-1435 P viral entry into host cell
A/B/C/D=1148-1435 P viral genome integration into host DNA
A/B/C/D=1148-1435 P viral penetration into host nucleus
Sequences
Download file with secondary structure created by Stride  
6puw.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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