General information
PDB ID 6U16
Title HUMAN THYMINE DNA GLYCOSYLASE N140A MUTANT BOUND TO DNA WITH 5- CARBOXYL-DC SUBSTRATE
PDB header HYDROLASE
Date 2019-08-15
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.6
Kind dna
Organism HOMO SAPIENS, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6u16.pdb A CD 0
Biounits:
6u16.pdb1.pdb A CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
UDG Domain Q13569_125-295 4.4e-19 1 No_clan A 125 296 CD  H-Bb H-Mj L-Bb L-Mj L-Mn 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=82-308 C nucleoplasm
A=82-308 C nucleus
A=82-308 C plasma membrane
A=82-308 C PML body
A=82-308 F ATP binding
A=82-308 F chloride ion binding
A=82-308 F damaged DNA binding
A=82-308 F DNA binding
A=82-308 F DNA N-glycosylase activity
A=82-308 F double-stranded DNA binding
A=82-308 F G/U mismatch-specific uracil-DNA glycosylase activity
A=82-308 F magnesium ion binding
A=82-308 F mismatched DNA binding
A=82-308 F protein domain specific binding
A=82-308 F protein homodimerization activity
A=82-308 F protein kinase C binding
A=82-308 F protein self-association
A=82-308 F pyrimidine-specific mismatch base pair DNA N-glycosylase activity
A=82-308 F sodium ion binding
A=82-308 F SUMO binding
A=82-308 F transcription coregulator activity
A=82-308 F transcription factor binding
A=82-308 F uracil DNA N-glycosylase activity
A=82-308 P base-excision repair
A=82-308 P base-excision repair, AP site formation
A=82-308 P chromatin organization
A=82-308 P depyrimidination
A=82-308 P DNA demethylation
A=82-308 P mismatch repair
A=82-308 P negative regulation of chromatin binding
A=82-308 P negative regulation of protein binding
A=82-308 P negative regulation of transcription by RNA polymerase II
A=82-308 P oxidative DNA demethylation
A=82-308 P regulation of DNA N-glycosylase activity
A=82-308 P regulation of embryonic development
A=82-308 P regulation of gene expression, epigenetic
Sequences
Download file with secondary structure created by Stride  
6u16.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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