General information
PDB ID 1AM9
Title HUMAN SREBP-1A BOUND TO LDL RECEPTOR PROMOTER
PDB header TRANSCRIPTION/DNA
Date 1997-06-25
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.3
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1am9.pdb ABCD EFGH 0
Biounits:
1am9.pdb1.pdb ABCD EFGH 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
HLH Domain P36956_324-374 5e-19 1 No_clan A 324 374 FG  H-Bb H-Mj L-Bb 
HLH Domain P36956_324-374 4.1e-19 1 No_clan B 324 374 FG  H-Bb H-Mj L-Bb 
HLH Domain P36956_324-374 5.4e-19 1 No_clan C 324 374 EH  H-Bb H-Mj L-Bb 
HLH Domain P36956_324-374 4.3e-19 1 No_clan D 324 374 EH  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
SREBP-1a A N/A N/A FG  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
SREBP-1a B N/A N/A FG  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
SREBP-1a C N/A N/A EH  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
SREBP-1a D N/A N/A EH  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A/B/C/D=319-400 C cytoplasm
A/B/C/D=319-400 C cytosol
A/B/C/D=319-400 C endoplasmic reticulum
A/B/C/D=319-400 C endoplasmic reticulum membrane
A/B/C/D=319-400 C ER to Golgi transport vesicle membrane
A/B/C/D=319-400 C Golgi membrane
A/B/C/D=319-400 C integral component of membrane
A/B/C/D=319-400 C nuclear chromatin
A/B/C/D=319-400 C nuclear envelope
A/B/C/D=319-400 C nucleoplasm
A/B/C/D=319-400 C nucleus
A/B/C/D=319-400 C protein-containing complex
A/B/C/D=319-400 F chromatin binding
A/B/C/D=319-400 F DNA binding
A/B/C/D=319-400 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B/C/D=319-400 F DNA-binding transcription factor activity
A/B/C/D=319-400 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B/C/D=319-400 F nuclear receptor activity
A/B/C/D=319-400 F protein dimerization activity
A/B/C/D=319-400 F protein kinase binding
A/B/C/D=319-400 F protein-containing complex binding
A/B/C/D=319-400 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B/C/D=319-400 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/B/C/D=319-400 F sequence-specific double-stranded DNA binding
A/B/C/D=319-400 F sterol response element binding
A/B/C/D=319-400 P aging
A/B/C/D=319-400 P cellular response to fatty acid
A/B/C/D=319-400 P cellular response to starvation
A/B/C/D=319-400 P cholesterol metabolic process
A/B/C/D=319-400 P circadian rhythm
A/B/C/D=319-400 P fat cell differentiation
A/B/C/D=319-400 P insulin receptor signaling pathway
A/B/C/D=319-400 P lipid biosynthetic process
A/B/C/D=319-400 P lipid localization
A/B/C/D=319-400 P lipid metabolic process
A/B/C/D=319-400 P lung development
A/B/C/D=319-400 P mRNA transcription by RNA polymerase II
A/B/C/D=319-400 P negative regulation of insulin secretion
A/B/C/D=319-400 P negative regulation of transcription by RNA polymerase II
A/B/C/D=319-400 P positive regulation of cholesterol biosynthetic process
A/B/C/D=319-400 P positive regulation of histone deacetylation
A/B/C/D=319-400 P positive regulation of pri-miRNA transcription by RNA polymerase II
A/B/C/D=319-400 P positive regulation of transcription by RNA polymerase II
A/B/C/D=319-400 P positive regulation of triglyceride biosynthetic process
A/B/C/D=319-400 P regulation of autophagy of mitochondrion
A/B/C/D=319-400 P regulation of cholesterol biosynthetic process
A/B/C/D=319-400 P regulation of fatty acid metabolic process
A/B/C/D=319-400 P regulation of heart rate by chemical signal
A/B/C/D=319-400 P regulation of lipid storage
A/B/C/D=319-400 P regulation of protein stability
A/B/C/D=319-400 P regulation of protein targeting to mitochondrion
A/B/C/D=319-400 P regulation of transcription by RNA polymerase II
A/B/C/D=319-400 P response to cAMP
A/B/C/D=319-400 P response to drug
A/B/C/D=319-400 P response to ethanol
A/B/C/D=319-400 P response to food
A/B/C/D=319-400 P response to glucagon
A/B/C/D=319-400 P response to glucose
A/B/C/D=319-400 P response to lipid
A/B/C/D=319-400 P response to progesterone
A/B/C/D=319-400 P response to retinoic acid
A/B/C/D=319-400 P SREBP signaling pathway
Sequences
Download file with secondary structure created by Stride  
1am9.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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G (dna): 
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H (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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