General information
PDB ID 1CF7
Title STRUCTURAL BASIS OF DNA RECOGNITION BY THE HETERODIMERIC CELL CYCLE TRANSCRIPTION FACTOR E2F-DP
PDB header TRANSCRIPTION/DNA
Date 1999-03-24
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.6
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1cf7.pdb AB CD 0
Biounits:
1cf7.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
E2F_TDP Domain Q16254_18-82 1.1e-26 1 CL0123 A 18 82 CD  H-Bb H-Mj L-Bb 
E2F_TDP Domain Q14188_129-208 5.9e-24 1 CL0123 B 68 147 CD  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Cell cycle transcription factor e2f-dp
Cell cycle transcription factor E2F-4 A N/A N/A CD  H-Bb H-Mj L-Bb L-Mn 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Cell cycle transcription factor e2f-dp
Cell cycle transcription factor DP-2 B N/A N/A CD  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A=11-86 C cytoplasm
A=11-86 C nuclear chromatin
A=11-86 C nucleoplasm
A=11-86 C nucleus
A=11-86 C RNA polymerase II transcription regulator complex
A=11-86 F DNA binding
A=11-86 F DNA-binding transcription activator activity
A=11-86 F DNA-binding transcription activator activity, RNA polymerase II-specific
A=11-86 F DNA-binding transcription factor activity
A=11-86 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=11-86 F promoter-specific chromatin binding
A=11-86 F protein dimerization activity
A=11-86 F protein domain specific binding
A=11-86 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A=11-86 F sequence-specific DNA binding
A=11-86 F sequence-specific double-stranded DNA binding
A=11-86 F transcription factor binding
A=11-86 P animal organ morphogenesis
A=11-86 P blood circulation
A=11-86 P cell volume homeostasis
A=11-86 P centriole assembly
A=11-86 P DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
A=11-86 P epithelial cell development
A=11-86 P motile cilium assembly
A=11-86 P multi-ciliated epithelial cell differentiation
A=11-86 P negative regulation of transcription by RNA polymerase II
A=11-86 P positive regulation of transcription by RNA polymerase II
A=11-86 P regulation of cell cycle
A=11-86 P regulation of cell population proliferation
A=11-86 P regulation of transcription involved in G1/S transition of mitotic cell cycle
B=121-215 C mitochondrion
B=121-215 C mitotic spindle
B=121-215 C nuclear chromatin
B=121-215 C nucleoplasm
B=121-215 C nucleus
B=121-215 C RNA polymerase II transcription regulator complex
B=121-215 F DNA binding
B=121-215 F DNA-binding transcription factor activity, RNA polymerase II-specific
B=121-215 F protein domain specific binding
B=121-215 F transcription factor binding
B=121-215 P DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
B=121-215 P heart development
B=121-215 P negative regulation of G0 to G1 transition
B=121-215 P negative regulation of transcription, DNA-templated
B=121-215 P positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
B=121-215 P positive regulation of transcription by RNA polymerase II
B=121-215 P regulation of transcription by RNA polymerase II
B=121-215 P regulation of transcription involved in G1/S transition of mitotic cell cycle
Sequences
Download file with secondary structure created by Stride  
1cf7.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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