General information
PDB ID 1EGW
Title CRYSTAL STRUCTURE OF MEF2A CORE BOUND TO DNA
PDB header TRANSCRIPTION/DNA
Date 2000-02-17
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.5
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1egw.pdb ABCD EFGH 0
Biounits:
1egw.pdb1.pdb AB EF 1
1egw.pdb2.pdb CD GH 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
SRF-TF Domain Q02078_10-57 1.7e-25 1 No_clan A 10 57 EF  H-Bb H-Mj 
SRF-TF Domain Q02078_10-57 1.8e-25 1 No_clan B 10 57 EF  H-Bb H-Mj 
SRF-TF Domain Q02078_10-57 1.8e-25 1 No_clan C 10 57 GH  H-Bb H-Mj 
SRF-TF Domain Q02078_10-57 1.7e-25 1 No_clan D 10 57 GH  H-Bb H-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a+b)
  Fold: SRF-like
    Superfamily: SRF-like
      Family: SRF-like
Myocyte enhancer factor Mef2a core A N/A N/A EF -
Class: Alpha and beta proteins (a+b)
  Fold: SRF-like
    Superfamily: SRF-like
      Family: SRF-like
Myocyte enhancer factor Mef2a core B N/A N/A EF -
Class: Alpha and beta proteins (a+b)
  Fold: SRF-like
    Superfamily: SRF-like
      Family: SRF-like
Myocyte enhancer factor Mef2a core C N/A N/A GH -
Class: Alpha and beta proteins (a+b)
  Fold: SRF-like
    Superfamily: SRF-like
      Family: SRF-like
Myocyte enhancer factor Mef2a core D N/A N/A GH -
GO terms
Protein chains: GO type: GO description:
A/B/C/D=2-78 C cytosol
A/B/C/D=2-78 C nuclear chromatin
A/B/C/D=2-78 C nucleoplasm
A/B/C/D=2-78 C nucleus
A/B/C/D=2-78 C transcription regulator complex
A/B/C/D=2-78 F activating transcription factor binding
A/B/C/D=2-78 F chromatin binding
A/B/C/D=2-78 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B/C/D=2-78 F DNA-binding transcription factor activity
A/B/C/D=2-78 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B/C/D=2-78 F histone acetyltransferase binding
A/B/C/D=2-78 F histone deacetylase binding
A/B/C/D=2-78 F protein heterodimerization activity
A/B/C/D=2-78 F protein kinase binding
A/B/C/D=2-78 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B/C/D=2-78 F RNA polymerase II transcription factor binding
A/B/C/D=2-78 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/B/C/D=2-78 F sequence-specific DNA binding
A/B/C/D=2-78 F SMAD binding
A/B/C/D=2-78 F transcription factor binding
A/B/C/D=2-78 F transcription regulatory region sequence-specific DNA binding
A/B/C/D=2-78 P apoptotic process
A/B/C/D=2-78 P cardiac conduction
A/B/C/D=2-78 P cell differentiation
A/B/C/D=2-78 P cellular response to calcium ion
A/B/C/D=2-78 P dendrite morphogenesis
A/B/C/D=2-78 P ERK5 cascade
A/B/C/D=2-78 P heart development
A/B/C/D=2-78 P MAPK cascade
A/B/C/D=2-78 P mitochondrial genome maintenance
A/B/C/D=2-78 P mitochondrion distribution
A/B/C/D=2-78 P muscle organ development
A/B/C/D=2-78 P negative regulation of transcription by RNA polymerase II
A/B/C/D=2-78 P positive regulation of cardiac muscle hypertrophy
A/B/C/D=2-78 P positive regulation of glucose import
A/B/C/D=2-78 P positive regulation of muscle cell differentiation
A/B/C/D=2-78 P positive regulation of transcription by RNA polymerase II
A/B/C/D=2-78 P transcription, DNA-templated
A/B/C/D=2-78 P ventricular cardiac myofibril assembly
Sequences
Download file with secondary structure created by Stride  
1egw.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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A (protein): 
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B (protein): 
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1egw.pdb2.pdb:   [ download sequences in FASTA format ]
G (dna): 
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H (dna): 
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C (protein): 
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D (protein): 
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