General information
PDB ID 1F2I
Title COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA
PDB header TRANSCRIPTION/DNA
Date 2000-05-25
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.35
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1f2i.pdb GHIJKL ABCDEF 0
Biounits:
1f2i.pdb1.pdb GH AB 1
1f2i.pdb2.pdb IJ CD 1
1f2i.pdb3.pdb KL EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-H2C2_2 Domain P08046_361-384 1.7e-08 0 CL0361 G 1121 1146 AB  H-Bb H-Mj S-Bb L-Bb 
zf-H2C2_2 Domain P08046_361-384 1.7e-08 0 CL0361 H 2121 2146 B  H-Bb H-Mj L-Bb 
zf-H2C2_2 Domain P08046_361-384 1.7e-08 0 CL0361 I 3121 3146 C  H-Bb H-Mj L-Bb 
zf-H2C2_2 Domain P08046_361-384 1.7e-08 0 CL0361 J 4121 4146 DC  H-Bb H-Mj S-Bb L-Bb 
zf-H2C2_2 Domain P08046_361-384 1.6e-08 0 CL0361 K 5121 5146 EF  H-Bb H-Mj 
zf-H2C2_2 Domain P08046_361-384 1.7e-08 0 CL0361 L 6121 6146 F  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 G 1093 1131 AB  H-Bb H-Mj S-Bb L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 G 1132 1158 AB  H-Bb H-Mj L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 H 2093 2131 B  H-Bb H-Mj S-Bb L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 H 2132 2158 AB  H-Bb H-Mj L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 I 3093 3131 CD  H-Bb H-Mj S-Bb L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 I 3132 3158 CD  H-Bb H-Mj L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 J 4093 4131 DC  H-Bb H-Mj L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 J 4132 4158 CD  H-Bb H-Mj L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 K 5096 5131 EF  H-Bb H-Mj L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 K 5132 5158 EF  H-Bb H-Mj L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 L 6093 6131 F  H-Bb H-Mj L-Bb L-Mj 
Class: Small proteins
  Fold: beta-beta-alpha zinc fingers
    Superfamily: beta-beta-alpha zinc fingers
      Family: Classic zinc finger, C2H2
ZIF268 L 6132 6158 EF  H-Bb H-Mj L-Bb L-Mj 
GO terms
Protein chains: GO type: GO description:
G/H/I/J/K/L=334-389 C cytoplasm
G/H/I/J/K/L=334-389 C nuclear chromatin
G/H/I/J/K/L=334-389 C nucleoplasm
G/H/I/J/K/L=334-389 C nucleus
G/H/I/J/K/L=334-389 F DNA binding
G/H/I/J/K/L=334-389 F DNA-binding transcription activator activity, RNA polymerase II-specific
G/H/I/J/K/L=334-389 F DNA-binding transcription factor activity
G/H/I/J/K/L=334-389 F DNA-binding transcription factor activity, RNA polymerase II-specific
G/H/I/J/K/L=334-389 F double-stranded DNA binding
G/H/I/J/K/L=334-389 F double-stranded methylated DNA binding
G/H/I/J/K/L=334-389 F hemi-methylated DNA-binding
G/H/I/J/K/L=334-389 F histone acetyltransferase binding
G/H/I/J/K/L=334-389 F promoter-specific chromatin binding
G/H/I/J/K/L=334-389 F RNA polymerase II core promoter sequence-specific DNA binding
G/H/I/J/K/L=334-389 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
G/H/I/J/K/L=334-389 F sequence-specific DNA binding
G/H/I/J/K/L=334-389 F sequence-specific double-stranded DNA binding
G/H/I/J/K/L=334-389 F transcription factor binding
G/H/I/J/K/L=334-389 F transcription regulatory region sequence-specific DNA binding
G/H/I/J/K/L=334-389 F zinc ion binding
G/H/I/J/K/L=334-389 P BMP signaling pathway
G/H/I/J/K/L=334-389 P cellular response to gamma radiation
G/H/I/J/K/L=334-389 P cellular response to heparin
G/H/I/J/K/L=334-389 P cellular response to interleukin-8
G/H/I/J/K/L=334-389 P cellular response to mycophenolic acid
G/H/I/J/K/L=334-389 P cellular response to organic substance
G/H/I/J/K/L=334-389 P circadian regulation of gene expression
G/H/I/J/K/L=334-389 P circadian temperature homeostasis
G/H/I/J/K/L=334-389 P estrous cycle
G/H/I/J/K/L=334-389 P glomerular mesangial cell proliferation
G/H/I/J/K/L=334-389 P interleukin-1-mediated signaling pathway
G/H/I/J/K/L=334-389 P learning or memory
G/H/I/J/K/L=334-389 P locomotor rhythm
G/H/I/J/K/L=334-389 P long-term memory
G/H/I/J/K/L=334-389 P negative regulation of canonical Wnt signaling pathway
G/H/I/J/K/L=334-389 P negative regulation of transcription by RNA polymerase II
G/H/I/J/K/L=334-389 P positive regulation of cell death
G/H/I/J/K/L=334-389 P positive regulation of chemokine biosynthetic process
G/H/I/J/K/L=334-389 P positive regulation of gene expression
G/H/I/J/K/L=334-389 P positive regulation of glomerular metanephric mesangial cell proliferation
G/H/I/J/K/L=334-389 P positive regulation of hormone biosynthetic process
G/H/I/J/K/L=334-389 P positive regulation of interleukin-1 beta production
G/H/I/J/K/L=334-389 P positive regulation of neuron apoptotic process
G/H/I/J/K/L=334-389 P positive regulation of neuron death
G/H/I/J/K/L=334-389 P positive regulation of pri-miRNA transcription by RNA polymerase II
G/H/I/J/K/L=334-389 P positive regulation of smooth muscle cell migration
G/H/I/J/K/L=334-389 P positive regulation of smooth muscle cell proliferation
G/H/I/J/K/L=334-389 P positive regulation of tau-protein kinase activity
G/H/I/J/K/L=334-389 P positive regulation of transcription by RNA polymerase II
G/H/I/J/K/L=334-389 P positive regulation of transcription, DNA-templated
G/H/I/J/K/L=334-389 P regulation of apoptotic process
G/H/I/J/K/L=334-389 P regulation of long-term neuronal synaptic plasticity
G/H/I/J/K/L=334-389 P regulation of progesterone biosynthetic process
G/H/I/J/K/L=334-389 P regulation of protein sumoylation
G/H/I/J/K/L=334-389 P regulation of transcription from RNA polymerase II promoter in response to hypoxia
G/H/I/J/K/L=334-389 P regulation of transcription, DNA-templated
G/H/I/J/K/L=334-389 P response to glucose
G/H/I/J/K/L=334-389 P response to hypoxia
G/H/I/J/K/L=334-389 P response to insulin
G/H/I/J/K/L=334-389 P response to ischemia
G/H/I/J/K/L=334-389 P skeletal muscle cell differentiation
G/H/I/J/K/L=334-389 P T cell differentiation
Sequences
Download file with secondary structure created by Stride  
1f2i.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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G (protein): 
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H (protein): 
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1f2i.pdb2.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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I (protein): 
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J (protein): 
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1f2i.pdb3.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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K (protein): 
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L (protein): 
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