General information
PDB ID 1H88
Title CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX1
PDB header TRANSCRIPTION/DNA
Date 2001-01-29
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.8
Kind dna
Organism HOMO SAPIENS, MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1h88.pdb ABC DE 0
Biounits:
1h88.pdb1.pdb ABC DE 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
bZIP_2 Coiled-coil P17676_270-323 3.1e-19 1 CL0018 A 270 323 DE  H-Bb H-Mj 
Taxilin Coiled-coil P17676_275-326 0.00014 0 No_clan A 276 336 DE  H-Bb H-Mj 
bZIP_2 Coiled-coil P17676_270-323 3.3e-19 1 CL0018 B 270 323 DE  H-Bb H-Mj 
Taxilin Coiled-coil P17676_275-326 0.00013 0 No_clan B 274 336 DE  H-Bb H-Mj 
Myb_DNA-binding Domain P06876_92-138 7.6e-19 1 CL0123 C 92 138 DE  H-Bb H-Mj L-Bb 
Myb_DNA-binding Domain P06876_40-86 6.1e-18 1 CL0123 C 40 86   
Myb_DNA-binding Domain P06876_144-189 1.7e-17 1 CL0123 C 144 189 DE  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Myb/SANT domain
c-Myb, DNA-binding domain C 39 88 -
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Myb/SANT domain
c-Myb, DNA-binding domain C 89 143 DE  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Myb/SANT domain
c-Myb, DNA-binding domain C 144 190 DE  H-Bb H-Mj L-Bb 
Class: Coiled coil proteins
  Fold: Parallel coiled-coil
    Superfamily: Leucine zipper domain
      Family: Leucine zipper domain
C/ebp beta A N/A N/A DE  H-Bb H-Mj L-Bb 
Class: Coiled coil proteins
  Fold: Parallel coiled-coil
    Superfamily: Leucine zipper domain
      Family: Leucine zipper domain
C/ebp beta B N/A N/A DE  H-Bb H-Mj 
GO terms
Protein chains: GO type: GO description:
A/B=259-336 C CHOP-C/EBP complex
A/B=259-336 C condensed chromosome, centromeric region
A/B=259-336 C cytoplasm
A/B=259-336 C nuclear chromatin
A/B=259-336 C nuclear matrix
A/B=259-336 C nucleoplasm
A/B=259-336 C nucleus
A/B=259-336 F chromatin binding
A/B=259-336 F DNA binding
A/B=259-336 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=259-336 F DNA-binding transcription factor activity
A/B=259-336 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=259-336 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A/B=259-336 F glucocorticoid receptor binding
A/B=259-336 F histone acetyltransferase binding
A/B=259-336 F histone deacetylase binding
A/B=259-336 F kinase binding
A/B=259-336 F protein heterodimerization activity
A/B=259-336 F protein homodimerization activity
A/B=259-336 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=259-336 F RNA polymerase II core promoter sequence-specific DNA binding
A/B=259-336 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/B=259-336 F sequence-specific double-stranded DNA binding
A/B=259-336 F ubiquitin-like protein ligase binding
A/B=259-336 P acute-phase response
A/B=259-336 P brown fat cell differentiation
A/B=259-336 P cellular response to amino acid stimulus
A/B=259-336 P cellular response to interleukin-1
A/B=259-336 P cellular response to lipopolysaccharide
A/B=259-336 P cellular response to organic cyclic compound
A/B=259-336 P defense response to bacterium
A/B=259-336 P embryonic placenta development
A/B=259-336 P granuloma formation
A/B=259-336 P hepatocyte proliferation
A/B=259-336 P immune response
A/B=259-336 P inflammatory response
A/B=259-336 P intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
A/B=259-336 P liver regeneration
A/B=259-336 P mammary gland epithelial cell differentiation
A/B=259-336 P mammary gland epithelial cell proliferation
A/B=259-336 P memory
A/B=259-336 P negative regulation of neuron apoptotic process
A/B=259-336 P negative regulation of T cell proliferation
A/B=259-336 P negative regulation of transcription by RNA polymerase II
A/B=259-336 P neuron differentiation
A/B=259-336 P ovarian follicle development
A/B=259-336 P positive regulation of biomineral tissue development
A/B=259-336 P positive regulation of cold-induced thermogenesis
A/B=259-336 P positive regulation of fat cell differentiation
A/B=259-336 P positive regulation of inflammatory response
A/B=259-336 P positive regulation of interleukin-4 production
A/B=259-336 P positive regulation of osteoblast differentiation
A/B=259-336 P positive regulation of sodium-dependent phosphate transport
A/B=259-336 P positive regulation of transcription by RNA polymerase II
A/B=259-336 P positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
A/B=259-336 P positive regulation of transcription, DNA-templated
A/B=259-336 P regulation of dendritic cell differentiation
A/B=259-336 P regulation of interleukin-6 production
A/B=259-336 P regulation of odontoblast differentiation
A/B=259-336 P regulation of osteoclast differentiation
A/B=259-336 P regulation of transcription involved in cell fate commitment
A/B=259-336 P regulation of transcription, DNA-templated
A/B=259-336 P response to endoplasmic reticulum stress
A/B=259-336 P T-helper 1 cell activation
C=37-193 C cytosol
C=37-193 C nucleoplasm
C=37-193 C nucleus
C=37-193 F DNA binding
C=37-193 F DNA-binding transcription activator activity, RNA polymerase II-specific
C=37-193 F DNA-binding transcription factor activity
C=37-193 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
C=37-193 F sequence-specific DNA binding
C=37-193 F transcription coregulator activity
C=37-193 F transcription regulatory region sequence-specific DNA binding
C=37-193 F WD40-repeat domain binding
C=37-193 P B cell differentiation
C=37-193 P calcium ion transport
C=37-193 P cellular response to interleukin-6
C=37-193 P cellular response to leukemia inhibitory factor
C=37-193 P chromatin remodeling
C=37-193 P embryonic digestive tract development
C=37-193 P G1/S transition of mitotic cell cycle
C=37-193 P homeostasis of number of cells
C=37-193 P in utero embryonic development
C=37-193 P mitotic cell cycle
C=37-193 P myeloid cell differentiation
C=37-193 P negative regulation of transcription by RNA polymerase II
C=37-193 P negative regulation of transcription, DNA-templated
C=37-193 P positive regulation of histone H3-K4 methylation
C=37-193 P positive regulation of histone H3-K9 methylation
C=37-193 P positive regulation of T-helper cell differentiation
C=37-193 P positive regulation of transcription by RNA polymerase II
C=37-193 P positive regulation of transcription, DNA-templated
C=37-193 P regulation of gene expression
C=37-193 P regulation of transcription, DNA-templated
C=37-193 P spleen development
C=37-193 P stem cell division
C=37-193 P thymus development
Sequences
Download file with secondary structure created by Stride  
1h88.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
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E (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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