General information
PDB ID 1H8A
Title CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX3
PDB header TRANSCRIPTION/DNA
Date 2001-01-31
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.23
Kind dna
Organism HOMO SAPIENS, AVIAN MYELOBLASTOSIS VIRUS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1h8a.pdb ABC DE 0
Biounits:
1h8a.pdb1.pdb ABC DE 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
bZIP_2 Coiled-coil P17676_270-323 2.8e-19 1 CL0018 A 270 323 DE  H-Bb H-Mj 
Taxilin Coiled-coil P17676_269-326 0.00038 0 No_clan A 276 334 DE  H-Bb H-Mj 
bZIP_2 Coiled-coil P17676_270-323 2.7e-19 1 CL0018 B 270 323 DE  H-Bb H-Mj 
Taxilin Coiled-coil P17676_269-326 0.00052 0 No_clan B 277 334 DE  H-Bb H-Mj 
Myb_DNA-bind_6 Domain P01104_10-67 1.8e-19 1 CL0123 C 95 152 DE  H-Bb H-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Myb/SANT domain
v-Myb C 87 143 DE  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Myb/SANT domain
v-Myb C 144 191 DE  H-Bb H-Mj L-Bb 
Class: Coiled coil proteins
  Fold: Parallel coiled-coil
    Superfamily: Leucine zipper domain
      Family: Leucine zipper domain
C/ebp beta A N/A N/A DE  H-Bb H-Mj L-Bb 
Class: Coiled coil proteins
  Fold: Parallel coiled-coil
    Superfamily: Leucine zipper domain
      Family: Leucine zipper domain
C/ebp beta B N/A N/A DE  H-Bb H-Mj 
GO terms
Protein chains: GO type: GO description:
A/B=259-336 C CHOP-C/EBP complex
A/B=259-336 C condensed chromosome, centromeric region
A/B=259-336 C cytoplasm
A/B=259-336 C nuclear chromatin
A/B=259-336 C nuclear matrix
A/B=259-336 C nucleoplasm
A/B=259-336 C nucleus
A/B=259-336 F chromatin binding
A/B=259-336 F DNA binding
A/B=259-336 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=259-336 F DNA-binding transcription factor activity
A/B=259-336 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=259-336 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A/B=259-336 F glucocorticoid receptor binding
A/B=259-336 F histone acetyltransferase binding
A/B=259-336 F histone deacetylase binding
A/B=259-336 F kinase binding
A/B=259-336 F protein heterodimerization activity
A/B=259-336 F protein homodimerization activity
A/B=259-336 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=259-336 F RNA polymerase II core promoter sequence-specific DNA binding
A/B=259-336 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/B=259-336 F sequence-specific double-stranded DNA binding
A/B=259-336 F ubiquitin-like protein ligase binding
A/B=259-336 P acute-phase response
A/B=259-336 P brown fat cell differentiation
A/B=259-336 P cellular response to amino acid stimulus
A/B=259-336 P cellular response to interleukin-1
A/B=259-336 P cellular response to lipopolysaccharide
A/B=259-336 P cellular response to organic cyclic compound
A/B=259-336 P defense response to bacterium
A/B=259-336 P embryonic placenta development
A/B=259-336 P granuloma formation
A/B=259-336 P hepatocyte proliferation
A/B=259-336 P immune response
A/B=259-336 P inflammatory response
A/B=259-336 P intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
A/B=259-336 P liver regeneration
A/B=259-336 P mammary gland epithelial cell differentiation
A/B=259-336 P mammary gland epithelial cell proliferation
A/B=259-336 P memory
A/B=259-336 P negative regulation of neuron apoptotic process
A/B=259-336 P negative regulation of T cell proliferation
A/B=259-336 P negative regulation of transcription by RNA polymerase II
A/B=259-336 P neuron differentiation
A/B=259-336 P ovarian follicle development
A/B=259-336 P positive regulation of biomineral tissue development
A/B=259-336 P positive regulation of cold-induced thermogenesis
A/B=259-336 P positive regulation of fat cell differentiation
A/B=259-336 P positive regulation of inflammatory response
A/B=259-336 P positive regulation of interleukin-4 production
A/B=259-336 P positive regulation of osteoblast differentiation
A/B=259-336 P positive regulation of sodium-dependent phosphate transport
A/B=259-336 P positive regulation of transcription by RNA polymerase II
A/B=259-336 P positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
A/B=259-336 P positive regulation of transcription, DNA-templated
A/B=259-336 P regulation of dendritic cell differentiation
A/B=259-336 P regulation of interleukin-6 production
A/B=259-336 P regulation of odontoblast differentiation
A/B=259-336 P regulation of osteoclast differentiation
A/B=259-336 P regulation of transcription involved in cell fate commitment
A/B=259-336 P regulation of transcription, DNA-templated
A/B=259-336 P response to endoplasmic reticulum stress
A/B=259-336 P T-helper 1 cell activation
C=1-122 C host cell nucleus
C=1-122 F DNA binding
C=1-122 P regulation of transcription, DNA-templated
Sequences
Download file with secondary structure created by Stride  
1h8a.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
Click "SHOW" for view sequence
E (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
C (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text