General information
PDB ID 1IG7
Title MSX-1 HOMEODOMAIN/DNA COMPLEX STRUCTURE
PDB header TRANSCRIPTION/DNA
Date 2001-04-17
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.2
Kind dna
Organism MUS MUSCULUS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1ig7.pdb A BC 0
Biounits:
1ig7.pdb1.pdb A BC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Homeodomain Domain P13297_173-229 1.3e-22 1 CL0123 A 102 158 BC  H-Bb H-Mj L-Bb L-Mn 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Msx-1 homeodomain A N/A N/A BC  H-Bb H-Mj L-Bb L-Mn 
GO terms
Protein chains: GO type: GO description:
A=173-230 C nucleoplasm
A=173-230 C nucleus
A=173-230 F cis-regulatory region sequence-specific DNA binding
A=173-230 F DNA-binding transcription activator activity, RNA polymerase II-specific
A=173-230 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=173-230 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A=173-230 F p53 binding
A=173-230 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A=173-230 F sequence-specific DNA binding
A=173-230 F sequence-specific double-stranded DNA binding
A=173-230 P activation of meiosis
A=173-230 P anterior/posterior pattern specification
A=173-230 P BMP signaling pathway
A=173-230 P BMP signaling pathway involved in heart development
A=173-230 P bone morphogenesis
A=173-230 P cartilage development
A=173-230 P cartilage morphogenesis
A=173-230 P cell morphogenesis
A=173-230 P cellular response to nicotine
A=173-230 P embryonic digit morphogenesis
A=173-230 P embryonic forelimb morphogenesis
A=173-230 P embryonic hindlimb morphogenesis
A=173-230 P embryonic limb morphogenesis
A=173-230 P embryonic morphogenesis
A=173-230 P embryonic nail plate morphogenesis
A=173-230 P epithelial to mesenchymal transition
A=173-230 P epithelial to mesenchymal transition involved in endocardial cushion formation
A=173-230 P face morphogenesis
A=173-230 P forebrain development
A=173-230 P heart development
A=173-230 P heart morphogenesis
A=173-230 P in utero embryonic development
A=173-230 P mammary gland epithelium development
A=173-230 P mesenchymal cell proliferation
A=173-230 P midbrain development
A=173-230 P middle ear morphogenesis
A=173-230 P muscle organ development
A=173-230 P negative regulation of apoptotic process
A=173-230 P negative regulation of cell growth
A=173-230 P negative regulation of cell population proliferation
A=173-230 P negative regulation of DNA binding
A=173-230 P negative regulation of striated muscle cell differentiation
A=173-230 P negative regulation of transcription by RNA polymerase II
A=173-230 P negative regulation of transcription regulatory region DNA binding
A=173-230 P negative regulation of transcription, DNA-templated
A=173-230 P odontogenesis
A=173-230 P odontogenesis of dentin-containing tooth
A=173-230 P pituitary gland development
A=173-230 P positive regulation of BMP signaling pathway
A=173-230 P positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
A=173-230 P positive regulation of mesenchymal cell apoptotic process
A=173-230 P positive regulation of transcription by RNA polymerase II
A=173-230 P protein localization to nucleus
A=173-230 P protein stabilization
A=173-230 P regulation of odontogenesis
A=173-230 P roof of mouth development
A=173-230 P signal transduction involved in regulation of gene expression
A=173-230 P stem cell differentiation
Sequences
Download file with secondary structure created by Stride  
1ig7.pdb1.pdb:   [ download sequences in FASTA format ]
B (dna): 
Click "SHOW" for view sequence
C (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text