General information
PDB ID 1JEY
Title CRYSTAL STRUCTURE OF THE KU HETERODIMER BOUND TO DNA
PDB header DNA BINDING PROTEIN/DNA
Date 2001-06-19
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.5
Kind dna
Organism HOMO SAPIENS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1jey.pdb AB CD 0
Biounits:
1jey.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Ku_N Domain P12956_37-256 7.8e-73 1 CL0128 A 37 256   
Ku Domain P12956_263-468 1.1e-50 1 CL0616 A 263 468 CD  L-Bb 
Ku_N Domain P13010_9-244 9.4e-62 1 CL0128 B 9 244 D  L-Bb 
Ku Domain P13010_253-453 1e-43 1 CL0616 B 253 453 CD  S-Bb L-Bb L-Mn 
Ku_C Family P12956_472-534 9.1e-23 1 No_clan A 472 534   
Ku_C Family P13010_476-545 5.8e-12 1 No_clan B 476 545 C  H-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All beta proteins
  Fold: SPOC domain-like
    Superfamily: SPOC domain-like
      Family: Ku70 subunit middle domain
Ku70 subunit middle domain A 254 534 CD -
Class: Alpha and beta proteins (a/b)
  Fold: vWA-like
    Superfamily: vWA-like
      Family: Ku70 subunit N-terminal domain
Ku70 subunit N-terminal domain A 34 253 -
Class: All beta proteins
  Fold: SPOC domain-like
    Superfamily: SPOC domain-like
      Family: Ku80 subunit middle domain
Ku80 subunit middle domain B 242 545 CD -
Class: Alpha and beta proteins (a/b)
  Fold: vWA-like
    Superfamily: vWA-like
      Family: Ku80 subunit N-terminal domain
Ku80 subunit N-terminal domain B 6 241 D -
GO terms
Protein chains: GO type: GO description:
A=1-609 C cytosol
A=1-609 C extracellular region
A=1-609 C ficolin-1-rich granule lumen
A=1-609 C Ku70:Ku80 complex
A=1-609 C membrane
A=1-609 C nonhomologous end joining complex
A=1-609 C nuclear chromosome, telomeric region
A=1-609 C nuclear telomere cap complex
A=1-609 C nucleolus
A=1-609 C nucleoplasm
A=1-609 C nucleus
A=1-609 C protein-containing complex
A=1-609 C protein-DNA complex
A=1-609 C secretory granule lumen
A=1-609 C transcription regulator complex
A=1-609 F 5'-deoxyribose-5-phosphate lyase activity
A=1-609 F ATP binding
A=1-609 F cyclin binding
A=1-609 F damaged DNA binding
A=1-609 F DNA binding
A=1-609 F DNA helicase activity
A=1-609 F double-stranded DNA binding
A=1-609 F protein C-terminus binding
A=1-609 F protein-containing complex binding
A=1-609 F RNA binding
A=1-609 F telomeric DNA binding
A=1-609 F transcription regulatory region sequence-specific DNA binding
A=1-609 P activation of innate immune response
A=1-609 P brain development
A=1-609 P cellular hyperosmotic salinity response
A=1-609 P cellular response to gamma radiation
A=1-609 P cellular response to X-ray
A=1-609 P DNA ligation
A=1-609 P DNA recombination
A=1-609 P double-strand break repair via classical nonhomologous end joining
A=1-609 P double-strand break repair via nonhomologous end joining
A=1-609 P establishment of integrated proviral latency
A=1-609 P innate immune response
A=1-609 P negative regulation of transcription, DNA-templated
A=1-609 P neutrophil degranulation
A=1-609 P positive regulation of lymphocyte differentiation
A=1-609 P positive regulation of protein kinase activity
A=1-609 P positive regulation of transcription by RNA polymerase II
A=1-609 P positive regulation of transcription, DNA-templated
A=1-609 P positive regulation of type I interferon production
A=1-609 P regulation of smooth muscle cell proliferation
A=1-609 P telomere maintenance
B=1-565 C cytosol
B=1-565 C extracellular region
B=1-565 C Ku70:Ku80 complex
B=1-565 C membrane
B=1-565 C nonhomologous end joining complex
B=1-565 C nuclear chromosome, telomeric region
B=1-565 C nuclear telomere cap complex
B=1-565 C nucleolus
B=1-565 C nucleoplasm
B=1-565 C nucleus
B=1-565 C plasma membrane
B=1-565 C protein-containing complex
B=1-565 C protein-DNA complex
B=1-565 C ribonucleoprotein complex
B=1-565 C secretory granule lumen
B=1-565 C site of DNA damage
B=1-565 C small-subunit processome
B=1-565 F ATP binding
B=1-565 F damaged DNA binding
B=1-565 F DNA binding
B=1-565 F DNA end binding
B=1-565 F DNA helicase activity
B=1-565 F double-stranded DNA binding
B=1-565 F enzyme activator activity
B=1-565 F protein C-terminus binding
B=1-565 F protein-containing complex binding
B=1-565 F RNA binding
B=1-565 F telomeric DNA binding
B=1-565 F transcription regulatory region sequence-specific DNA binding
B=1-565 F U3 snoRNA binding
B=1-565 F ubiquitin protein ligase binding
B=1-565 P activation of innate immune response
B=1-565 P brain development
B=1-565 P cell population proliferation
B=1-565 P cellular hyperosmotic salinity response
B=1-565 P cellular response to DNA damage stimulus
B=1-565 P cellular response to fatty acid
B=1-565 P cellular response to gamma radiation
B=1-565 P cellular response to leukemia inhibitory factor
B=1-565 P cellular response to X-ray
B=1-565 P DNA recombination
B=1-565 P double-strand break repair
B=1-565 P double-strand break repair via nonhomologous end joining
B=1-565 P establishment of integrated proviral latency
B=1-565 P hematopoietic stem cell differentiation
B=1-565 P innate immune response
B=1-565 P negative regulation of t-circle formation
B=1-565 P negative regulation of transcription, DNA-templated
B=1-565 P neutrophil degranulation
B=1-565 P positive regulation of catalytic activity
B=1-565 P positive regulation of neurogenesis
B=1-565 P positive regulation of protein kinase activity
B=1-565 P positive regulation of telomerase activity
B=1-565 P positive regulation of telomere maintenance via telomerase
B=1-565 P positive regulation of type I interferon production
B=1-565 P protein localization to chromosome, telomeric region
B=1-565 P regulation of smooth muscle cell proliferation
B=1-565 P regulation of telomere maintenance
B=1-565 P response to drug
B=1-565 P small-subunit processome assembly
B=1-565 P telomere maintenance
Sequences
Download file with secondary structure created by Stride  
1jey.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
Click "SHOW" for view sequence
D (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text