General information
PDB ID 1NKP
Title CRYSTAL STRUCTURE OF MYC-MAX RECOGNIZING DNA
PDB header TRANSCRIPTION/DNA
Date 2003-01-03
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.8
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1nkp.pdb ABDE FGHJ 0
Biounits:
1nkp.pdb1.pdb AB FG 1
1nkp.pdb2.pdb DE HJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Myc-LZ Coiled-coil P01106_408-434 4.6e-15 1 No_clan A 955 984   
Myc-LZ Coiled-coil P01106_408-434 1.2e-12 1 No_clan D 555 581   
HLH Domain P01106_355-407 2e-15 1 No_clan A 902 954 FG  H-Bb H-Mj L-Bb 
HLH Domain P61244_24-75 7.6e-18 1 No_clan B 203 254 FG  H-Bb H-Mj 
HLH Domain P01106_355-407 1.7e-15 1 No_clan D 502 554 HJ  H-Bb H-Mj 
HLH Domain P61244_24-75 2e-17 1 No_clan E 704 754 HJ  H-Bb H-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Max protein B N/A N/A FG  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Myc proto-oncogene protein A N/A N/A FG  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Max protein E N/A N/A HJ  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Myc proto-oncogene protein D N/A N/A HJ  H-Bb H-Mj 
GO terms
Protein chains: GO type: GO description:
A/D=353-434 C host cell nucleus
A/D=353-434 C nuclear chromatin
A/D=353-434 C nucleolus
A/D=353-434 C nucleoplasm
A/D=353-434 C nucleus
A/D=353-434 C protein-containing complex
A/D=353-434 F activating transcription factor binding
A/D=353-434 F core promoter sequence-specific DNA binding
A/D=353-434 F DNA binding
A/D=353-434 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/D=353-434 F DNA-binding transcription factor activity
A/D=353-434 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/D=353-434 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A/D=353-434 F E-box binding
A/D=353-434 F protein dimerization activity
A/D=353-434 F protein-containing complex binding
A/D=353-434 F repressing transcription factor binding
A/D=353-434 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/D=353-434 F transcription factor binding
A/D=353-434 P beta-catenin-TCF complex assembly
A/D=353-434 P branching involved in ureteric bud morphogenesis
A/D=353-434 P cell cycle arrest
A/D=353-434 P cellular iron ion homeostasis
A/D=353-434 P cellular response to DNA damage stimulus
A/D=353-434 P cellular response to drug
A/D=353-434 P cellular response to hypoxia
A/D=353-434 P cellular response to UV
A/D=353-434 P chromatin remodeling
A/D=353-434 P chromosome organization
A/D=353-434 P cytokine-mediated signaling pathway
A/D=353-434 P energy reserve metabolic process
A/D=353-434 P ERK1 and ERK2 cascade
A/D=353-434 P fibroblast apoptotic process
A/D=353-434 P G1/S transition of mitotic cell cycle
A/D=353-434 P MAPK cascade
A/D=353-434 P negative regulation of apoptotic process
A/D=353-434 P negative regulation of cell division
A/D=353-434 P negative regulation of fibroblast proliferation
A/D=353-434 P negative regulation of monocyte differentiation
A/D=353-434 P negative regulation of stress-activated MAPK cascade
A/D=353-434 P negative regulation of transcription by RNA polymerase II
A/D=353-434 P Notch signaling pathway
A/D=353-434 P oxygen transport
A/D=353-434 P positive regulation of cell population proliferation
A/D=353-434 P positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
A/D=353-434 P positive regulation of DNA biosynthetic process
A/D=353-434 P positive regulation of DNA methylation
A/D=353-434 P positive regulation of epithelial cell proliferation
A/D=353-434 P positive regulation of fibroblast proliferation
A/D=353-434 P positive regulation of gene expression
A/D=353-434 P positive regulation of mesenchymal cell proliferation
A/D=353-434 P positive regulation of metanephric cap mesenchymal cell proliferation
A/D=353-434 P positive regulation of response to DNA damage stimulus
A/D=353-434 P positive regulation of telomerase activity
A/D=353-434 P positive regulation of transcription by RNA polymerase II
A/D=353-434 P positive regulation of transcription, DNA-templated
A/D=353-434 P protein deubiquitination
A/D=353-434 P protein-DNA complex disassembly
A/D=353-434 P regulation of gene expression
A/D=353-434 P regulation of somatic stem cell population maintenance
A/D=353-434 P regulation of telomere maintenance
A/D=353-434 P regulation of transcription by RNA polymerase II
A/D=353-434 P response to drug
A/D=353-434 P response to gamma radiation
A/D=353-434 P response to growth factor
B/E=23-102 C cytoplasm
B/E=23-102 C dendrite
B/E=23-102 C MLL1 complex
B/E=23-102 C nuclear chromatin
B/E=23-102 C nucleoplasm
B/E=23-102 C nucleus
B/E=23-102 C PML body
B/E=23-102 C protein-DNA complex
B/E=23-102 C RNA polymerase II transcription regulator complex
B/E=23-102 F DNA binding
B/E=23-102 F DNA-binding transcription factor activity
B/E=23-102 F DNA-binding transcription factor activity, RNA polymerase II-specific
B/E=23-102 F DNA-binding transcription repressor activity, RNA polymerase II-specific
B/E=23-102 F E-box binding
B/E=23-102 F identical protein binding
B/E=23-102 F protein dimerization activity
B/E=23-102 F protein-containing complex binding
B/E=23-102 F sequence-specific double-stranded DNA binding
B/E=23-102 P cellular response to peptide hormone stimulus
B/E=23-102 P cellular response to starvation
B/E=23-102 P G1/S transition of mitotic cell cycle
B/E=23-102 P negative regulation of G0 to G1 transition
B/E=23-102 P negative regulation of transcription by RNA polymerase II
B/E=23-102 P neuron apoptotic process
B/E=23-102 P positive regulation of transcription by RNA polymerase II
B/E=23-102 P protein-containing complex assembly
B/E=23-102 P regulation of transcription by RNA polymerase II
B/E=23-102 P response to axon injury
B/E=23-102 P response to insulin
B/E=23-102 P retina development in camera-type eye
Sequences
Download file with secondary structure created by Stride  
1nkp.pdb1.pdb:   [ download sequences in FASTA format ]
F (dna): 
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G (dna): 
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A (protein): 
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B (protein): 
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1nkp.pdb2.pdb:   [ download sequences in FASTA format ]
H (dna): 
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J (dna): 
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D (protein): 
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E (protein): 
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