General information
PDB ID 1NLW
Title CRYSTAL STRUCTURE OF MAD-MAX RECOGNIZING DNA
PDB header TRANSCRIPTION/DNA
Date 2003-01-07
Experimental method X-RAY DIFFRACTION
Resolution (A) 2
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1nlw.pdb ABDE FGHJ 0
Biounits:
1nlw.pdb1.pdb AB FG 1
1nlw.pdb2.pdb DE HJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
HLH Domain Q05195_57-109 7.3e-13 1 No_clan A 2 54 FG  H-Bb H-Mj L-Bb 
HLH Domain P61244_24-75 5.8e-18 1 No_clan B 203 254 FG  H-Bb H-Mj L-Bb 
HLH Domain Q05195_57-109 6.8e-13 1 No_clan D 502 554 HJ  H-Bb H-Mj L-Bb 
HLH Domain P61244_24-75 6.3e-17 1 No_clan E 705 754 HJ  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Max protein B N/A N/A FG  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Mad protein A N/A N/A FG  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Max protein E N/A N/A HJ  H-Bb H-Mj 
Class: All alpha proteins
  Fold: HLH-like
    Superfamily: HLH, helix-loop-helix DNA-binding domain
      Family: HLH, helix-loop-helix DNA-binding domain
Mad protein D N/A N/A HJ  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A/D=57-136 C cytosol
A/D=57-136 C mitochondrion
A/D=57-136 C nuclear chromatin
A/D=57-136 C nucleoplasm
A/D=57-136 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/D=57-136 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A/D=57-136 F protein dimerization activity
A/D=57-136 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/D=57-136 P negative regulation of transcription by RNA polymerase II
B/E=24-99 C cytoplasm
B/E=24-99 C dendrite
B/E=24-99 C MLL1 complex
B/E=24-99 C nuclear chromatin
B/E=24-99 C nucleoplasm
B/E=24-99 C nucleus
B/E=24-99 C PML body
B/E=24-99 C protein-DNA complex
B/E=24-99 C RNA polymerase II transcription regulator complex
B/E=24-99 F DNA binding
B/E=24-99 F DNA-binding transcription factor activity
B/E=24-99 F DNA-binding transcription factor activity, RNA polymerase II-specific
B/E=24-99 F DNA-binding transcription repressor activity, RNA polymerase II-specific
B/E=24-99 F E-box binding
B/E=24-99 F identical protein binding
B/E=24-99 F protein dimerization activity
B/E=24-99 F protein-containing complex binding
B/E=24-99 F sequence-specific double-stranded DNA binding
B/E=24-99 P cellular response to peptide hormone stimulus
B/E=24-99 P cellular response to starvation
B/E=24-99 P G1/S transition of mitotic cell cycle
B/E=24-99 P negative regulation of G0 to G1 transition
B/E=24-99 P negative regulation of transcription by RNA polymerase II
B/E=24-99 P neuron apoptotic process
B/E=24-99 P positive regulation of transcription by RNA polymerase II
B/E=24-99 P protein-containing complex assembly
B/E=24-99 P regulation of transcription by RNA polymerase II
B/E=24-99 P response to axon injury
B/E=24-99 P response to insulin
B/E=24-99 P retina development in camera-type eye
Sequences
Download file with secondary structure created by Stride  
1nlw.pdb1.pdb:   [ download sequences in FASTA format ]
F (dna): 
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G (dna): 
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A (protein): 
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B (protein): 
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1nlw.pdb2.pdb:   [ download sequences in FASTA format ]
H (dna): 
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J (dna): 
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D (protein): 
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E (protein): 
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