General information
PDB ID 1PUF
Title CRYSTAL STRUCTURE OF HOXA9 AND PBX1 HOMEODOMAINS BOUND TO DNA
PDB header TRANSCRIPTION/DNA
Date 2003-06-24
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.9
Kind dna
Organism MUS MUSCULUS, HOMO SAPIENS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1puf.pdb AB DE 0
Biounits:
1puf.pdb1.pdb AB DE 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Homeodomain Domain P09631_206-262 9.1e-22 1 CL0123 A 206 262 DE  H-Bb H-Mj L-Bb L-Mn 
Homeodomain Domain P40424_235-293 6.8e-21 1 CL0123 B 234 293 DE  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Homeobox protein hox-a9 A N/A N/A DE  H-Bb H-Mj L-Bb L-Mn 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
pbx1 B N/A N/A DE  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A=193-269 C cytoplasm
A=193-269 C nucleoplasm
A=193-269 C nucleus
A=193-269 C transcription regulator complex
A=193-269 F DNA-binding transcription activator activity, RNA polymerase II-specific
A=193-269 F DNA-binding transcription factor activity
A=193-269 F enzyme binding
A=193-269 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A=193-269 F sequence-specific double-stranded DNA binding
A=193-269 P anterior/posterior pattern specification
A=193-269 P definitive hemopoiesis
A=193-269 P embryonic forelimb morphogenesis
A=193-269 P embryonic skeletal system development
A=193-269 P embryonic skeletal system morphogenesis
A=193-269 P endothelial cell activation
A=193-269 P male gonad development
A=193-269 P mammary gland development
A=193-269 P negative regulation of myeloid cell differentiation
A=193-269 P positive regulation of transcription by RNA polymerase II
A=193-269 P proximal/distal pattern formation
A=193-269 P regulation of gene expression
A=193-269 P single fertilization
A=193-269 P spermatogenesis
A=193-269 P transcription, DNA-templated
A=193-269 P uterus development
B=233-305 C cytoplasm
B=233-305 C nuclear chromatin
B=233-305 C nucleoplasm
B=233-305 C nucleus
B=233-305 C RNA polymerase II transcription regulator complex
B=233-305 F DNA binding
B=233-305 F DNA-binding transcription activator activity, RNA polymerase II-specific
B=233-305 F DNA-binding transcription factor activity
B=233-305 F DNA-binding transcription factor activity, RNA polymerase II-specific
B=233-305 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
B=233-305 F sequence-specific double-stranded DNA binding
B=233-305 F transcription factor binding
B=233-305 P adrenal gland development
B=233-305 P animal organ morphogenesis
B=233-305 P anterior/posterior pattern specification
B=233-305 P brain development
B=233-305 P branching involved in ureteric bud morphogenesis
B=233-305 P embryonic hemopoiesis
B=233-305 P embryonic limb morphogenesis
B=233-305 P embryonic organ development
B=233-305 P embryonic skeletal system development
B=233-305 P eye development
B=233-305 P negative regulation of DNA-binding transcription factor activity
B=233-305 P negative regulation of neuron differentiation
B=233-305 P neuron development
B=233-305 P positive regulation of cell population proliferation
B=233-305 P positive regulation of G2/M transition of mitotic cell cycle
B=233-305 P positive regulation of transcription of Notch receptor target
B=233-305 P proximal/distal pattern formation
B=233-305 P regulation of ossification
B=233-305 P sex differentiation
B=233-305 P somatic stem cell population maintenance
B=233-305 P spleen development
B=233-305 P steroid biosynthetic process
B=233-305 P thymus development
Sequences
Download file with secondary structure created by Stride  
1puf.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
Click "SHOW" for view sequence
E (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text