General information
PDB ID 1R0N
Title CRYSTAL STRUCTURE OF HETERODIMERIC ECDSYONE RECEPTOR DNA BINDING COMPLEX
PDB header TRANSCRIPTION/DNA
Date 2003-09-22
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.6
Kind dna
Organism HOMO SAPIENS, DROSOPHILA MELANOGASTER
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1r0n.pdb AB CD 0
Biounits:
1r0n.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-C4 Domain P19793_133-202 1.2e-33 1 CL0167 A 99 168 CD  H-Bb H-Mj S-Bb L-Bb L-Mj 
zf-C4 Domain P34021_262-331 1.6e-30 1 CL0167 B 199 268 CD  H-Bb H-Mj S-Bb L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Small proteins
  Fold: Glucocorticoid receptor-like (DNA-binding domain)
    Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
      Family: Nuclear receptor
Ecdysone receptor DNA-binding domain B N/A N/A CD  H-Bb H-Mj S-Bb L-Bb 
Class: Small proteins
  Fold: Glucocorticoid receptor-like (DNA-binding domain)
    Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
      Family: Nuclear receptor
Retinoid X receptor (RXR-alpha) DNA-binding domain A N/A N/A CD  H-Bb H-Mj S-Bb L-Bb 
GO terms
Protein chains: GO type: GO description:
A=130-206 C mitochondrion
A=130-206 C nuclear chromatin
A=130-206 C nucleoplasm
A=130-206 C nucleus
A=130-206 C protein-containing complex
A=130-206 C receptor complex
A=130-206 C RNA polymerase II transcription regulator complex
A=130-206 F chromatin DNA binding
A=130-206 F DNA binding domain binding
A=130-206 F DNA-binding transcription factor activity
A=130-206 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=130-206 F double-stranded DNA binding
A=130-206 F enzyme binding
A=130-206 F identical protein binding
A=130-206 F LBD domain binding
A=130-206 F nuclear receptor activity
A=130-206 F nuclear receptor binding
A=130-206 F peptide binding
A=130-206 F retinoic acid binding
A=130-206 F retinoic acid-responsive element binding
A=130-206 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A=130-206 F RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
A=130-206 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A=130-206 F sequence-specific DNA binding
A=130-206 F sequence-specific double-stranded DNA binding
A=130-206 F steroid hormone receptor activity
A=130-206 F transcription regulatory region sequence-specific DNA binding
A=130-206 F vitamin D receptor binding
A=130-206 F zinc ion binding
A=130-206 P anatomical structure development
A=130-206 P bile acid and bile salt transport
A=130-206 P camera-type eye development
A=130-206 P cardiac muscle cell proliferation
A=130-206 P cell differentiation
A=130-206 P cholesterol metabolic process
A=130-206 P embryo implantation
A=130-206 P in utero embryonic development
A=130-206 P maternal placenta development
A=130-206 P modulation by virus of host process
A=130-206 P negative regulation of transcription by RNA polymerase II
A=130-206 P peroxisome proliferator activated receptor signaling pathway
A=130-206 P positive regulation of transcription by RNA polymerase II
A=130-206 P positive regulation of transcription, DNA-templated
A=130-206 P positive regulation of translational initiation by iron
A=130-206 P regulation of branching involved in prostate gland morphogenesis
A=130-206 P regulation of lipid metabolic process
A=130-206 P regulation of transcription by RNA polymerase II
A=130-206 P response to retinoic acid
A=130-206 P retinoic acid receptor signaling pathway
A=130-206 P secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
A=130-206 P transcription initiation from RNA polymerase II promoter
A=130-206 P ventricular cardiac muscle cell differentiation
A=130-206 P ventricular cardiac muscle tissue morphogenesis
B=256-364 C activator ecdysone receptor complex
B=256-364 C cytoplasm
B=256-364 C dendrite
B=256-364 C ecdysone receptor holocomplex
B=256-364 C nucleus
B=256-364 C polytene chromosome
B=256-364 C repressor ecdysone receptor complex
B=256-364 C RNA polymerase II transcription regulator complex
B=256-364 F core promoter sequence-specific DNA binding
B=256-364 F DNA binding
B=256-364 F DNA-binding transcription activator activity, RNA polymerase II-specific
B=256-364 F DNA-binding transcription factor activity, RNA polymerase II-specific
B=256-364 F ecdysone binding
B=256-364 F nuclear receptor activity
B=256-364 F protein heterodimerization activity
B=256-364 F protein homodimerization activity
B=256-364 F repressing transcription factor binding
B=256-364 F RNA polymerase II transcription coactivator binding
B=256-364 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
B=256-364 F signaling receptor activity
B=256-364 F signaling receptor binding
B=256-364 F steroid binding
B=256-364 F transcription factor binding
B=256-364 F transcription regulatory region sequence-specific DNA binding
B=256-364 F zinc ion binding
B=256-364 P autophagy
B=256-364 P border follicle cell migration
B=256-364 P cardiac muscle tissue development
B=256-364 P cardioblast differentiation
B=256-364 P cell adhesion
B=256-364 P cell differentiation
B=256-364 P chitin-based cuticle development
B=256-364 P chitin-based embryonic cuticle biosynthetic process
B=256-364 P cholesterol homeostasis
B=256-364 P dendrite morphogenesis
B=256-364 P determination of adult lifespan
B=256-364 P dorsal vessel heart proper cell fate commitment
B=256-364 P ecdysis, chitin-based cuticle
B=256-364 P ecdysone receptor-mediated signaling pathway
B=256-364 P ecdysone-mediated induction of salivary gland cell autophagic cell death
B=256-364 P epidermis development
B=256-364 P germ cell development
B=256-364 P germ-band shortening
B=256-364 P hatching
B=256-364 P head involution
B=256-364 P histoblast morphogenesis
B=256-364 P imaginal disc-derived wing morphogenesis
B=256-364 P larval central nervous system remodeling
B=256-364 P larval development
B=256-364 P larval wandering behavior
B=256-364 P lipid homeostasis
B=256-364 P lipid metabolic process
B=256-364 P long-term memory
B=256-364 P Malpighian tubule morphogenesis
B=256-364 P metamorphosis
B=256-364 P mushroom body development
B=256-364 P negative regulation of transcription by RNA polymerase II
B=256-364 P negative regulation of transcription, DNA-templated
B=256-364 P neuron remodeling
B=256-364 P oogenesis
B=256-364 P peripheral nervous system development
B=256-364 P phagocytosis, engulfment
B=256-364 P positive regulation of apoptotic process
B=256-364 P positive regulation of circadian sleep/wake cycle, sleep
B=256-364 P positive regulation of neuron remodeling
B=256-364 P positive regulation of transcription by RNA polymerase II
B=256-364 P positive regulation of transcription, DNA-templated
B=256-364 P pupariation
B=256-364 P regulation of autophagy
B=256-364 P regulation of cellular respiration
B=256-364 P regulation of development, heterochronic
B=256-364 P regulation of hemocyte proliferation
B=256-364 P regulation of Malpighian tubule diameter
B=256-364 P regulation of neuron remodeling
B=256-364 P regulation of rhodopsin gene expression
B=256-364 P regulation of transcription by RNA polymerase II
B=256-364 P response to cocaine
B=256-364 P response to ecdysone
B=256-364 P salivary gland cell autophagic cell death
B=256-364 P sperm individualization
Sequences
Download file with secondary structure created by Stride  
1r0n.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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