General information
PDB ID 1R4I
Title CRYSTAL STRUCTURE OF ANDROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO A DIRECT REPEAT RESPONSE ELEMENT
PDB header TRANSCRIPTION/DNA
Date 2003-10-06
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.1
Kind dna
Organism RATTUS NORVEGICUS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1r4i.pdb AB CD 0
Biounits:
1r4i.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-C4 Domain P15207_540-609 1.6e-29 1 CL0167 A 540 609 CD  H-Bb H-Mj S-Bb L-Bb 
zf-C4 Domain P15207_540-609 1.4e-29 1 CL0167 B 540 609 CD  H-Bb H-Mj S-Bb L-Bb L-Mj 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Small proteins
  Fold: Glucocorticoid receptor-like (DNA-binding domain)
    Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
      Family: Nuclear receptor
Androgen receptor A N/A N/A CD  H-Bb H-Mj S-Bb L-Bb 
Class: Small proteins
  Fold: Glucocorticoid receptor-like (DNA-binding domain)
    Superfamily: Glucocorticoid receptor-like (DNA-binding domain)
      Family: Nuclear receptor
Androgen receptor B N/A N/A CD  H-Bb H-Mj S-Bb L-Bb 
GO terms
Protein chains: GO type: GO description:
A/B=533-637 C axon
A/B=533-637 C cytoplasm
A/B=533-637 C dendrite
A/B=533-637 C nuclear chromatin
A/B=533-637 C nuclear speck
A/B=533-637 C nucleus
A/B=533-637 C plasma membrane
A/B=533-637 C protein-containing complex
A/B=533-637 F androgen binding
A/B=533-637 F androgen receptor binding
A/B=533-637 F ATPase binding
A/B=533-637 F beta-catenin binding
A/B=533-637 F chromatin binding
A/B=533-637 F DNA binding
A/B=533-637 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=533-637 F DNA-binding transcription factor activity
A/B=533-637 F enzyme binding
A/B=533-637 F nuclear receptor activity
A/B=533-637 F POU domain binding
A/B=533-637 F protein domain specific binding
A/B=533-637 F repressing transcription factor binding
A/B=533-637 F ribonucleotide binding
A/B=533-637 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=533-637 F RNA polymerase II general transcription initiation factor binding
A/B=533-637 F RNA polymerase II transcription factor binding
A/B=533-637 F sequence-specific DNA binding
A/B=533-637 F signaling receptor binding
A/B=533-637 F steroid binding
A/B=533-637 F transcription factor binding
A/B=533-637 F transcription regulatory region sequence-specific DNA binding
A/B=533-637 F zinc ion binding
A/B=533-637 P activation of prostate induction by androgen receptor signaling pathway
A/B=533-637 P androgen receptor signaling pathway
A/B=533-637 P animal organ formation
A/B=533-637 P cellular process
A/B=533-637 P cellular response to follicle-stimulating hormone stimulus
A/B=533-637 P cellular response to steroid hormone stimulus
A/B=533-637 P cellular response to testosterone stimulus
A/B=533-637 P copulation
A/B=533-637 P epithelial cell differentiation involved in prostate gland development
A/B=533-637 P epithelial cell morphogenesis
A/B=533-637 P fertilization
A/B=533-637 P in utero embryonic development
A/B=533-637 P intracellular receptor signaling pathway
A/B=533-637 P lateral sprouting involved in mammary gland duct morphogenesis
A/B=533-637 P Leydig cell differentiation
A/B=533-637 P male courtship behavior
A/B=533-637 P male genitalia morphogenesis
A/B=533-637 P male gonad development
A/B=533-637 P male sex differentiation
A/B=533-637 P male somatic sex determination
A/B=533-637 P mammary gland alveolus development
A/B=533-637 P morphogenesis of an epithelial fold
A/B=533-637 P multicellular organism growth
A/B=533-637 P negative regulation of cell population proliferation
A/B=533-637 P negative regulation of epithelial cell proliferation
A/B=533-637 P negative regulation of extrinsic apoptotic signaling pathway
A/B=533-637 P negative regulation of integrin biosynthetic process
A/B=533-637 P negative regulation of transcription by RNA polymerase II
A/B=533-637 P negative regulation of transcription, DNA-templated
A/B=533-637 P positive regulation of cell differentiation
A/B=533-637 P positive regulation of cell population proliferation
A/B=533-637 P positive regulation of epithelial cell proliferation involved in prostate gland development
A/B=533-637 P positive regulation of gene expression
A/B=533-637 P positive regulation of insulin-like growth factor receptor signaling pathway
A/B=533-637 P positive regulation of integrin biosynthetic process
A/B=533-637 P positive regulation of intracellular estrogen receptor signaling pathway
A/B=533-637 P positive regulation of MAPK cascade
A/B=533-637 P positive regulation of NF-kappaB transcription factor activity
A/B=533-637 P positive regulation of penile erection
A/B=533-637 P positive regulation of phosphorylation
A/B=533-637 P positive regulation of transcription by RNA polymerase II
A/B=533-637 P positive regulation of transcription by RNA polymerase III
A/B=533-637 P positive regulation of transcription, DNA-templated
A/B=533-637 P prostate gland epithelium morphogenesis
A/B=533-637 P prostate gland growth
A/B=533-637 P regulation of developmental growth
A/B=533-637 P regulation of gene expression
A/B=533-637 P regulation of prostatic bud formation
A/B=533-637 P regulation of protein localization to plasma membrane
A/B=533-637 P regulation of systemic arterial blood pressure
A/B=533-637 P regulation of transcription by RNA polymerase II
A/B=533-637 P regulation of transcription, DNA-templated
A/B=533-637 P reproductive behavior
A/B=533-637 P reproductive structure development
A/B=533-637 P reproductive system development
A/B=533-637 P response to estradiol
A/B=533-637 P response to insulin
A/B=533-637 P response to testosterone
A/B=533-637 P seminiferous tubule development
A/B=533-637 P single fertilization
A/B=533-637 P skeletal muscle hypertrophy
A/B=533-637 P spermatogenesis
A/B=533-637 P tertiary branching involved in mammary gland duct morphogenesis
A/B=533-637 P transcription, DNA-templated
Sequences
Download file with secondary structure created by Stride  
1r4i.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
Click "SHOW" for view sequence
D (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text