General information
PDB ID 1T39
Title HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE COVALENTLY CROSSLINKED TO DNA
PDB header TRANSFERASE/DNA
Date 2004-04-25
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.3
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1t39.pdb AB CDEF 0
Biounits:
1t39.pdb1.pdb A CD 1
1t39.pdb2.pdb B EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
DNA_binding_1 Domain P16455_93-174 1.7e-28 1 No_clan A 93 174 CD  H-Bb H-Mj H-Mn L-Bb 
Methyltransf_1N Domain P16455_6-90 7.9e-15 1 No_clan A 6 90   
DNA_binding_1 Domain P16455_93-174 1.6e-28 1 No_clan B 93 174 EF  H-Bb H-Mj H-Mn L-Bb 
Methyltransf_1N Domain P16455_6-90 1.6e-14 1 No_clan B 7 90   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Methylated DNA-protein cysteine methyltransferase, C-terminal domain
      Family: Methylated DNA-protein cysteine methyltransferase, C-terminal domain
O6-alkylguanine-DNA alkyltransferase A 92 175 CD  H-Bb H-Mj H-Mn L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Methylated DNA-protein cysteine methyltransferase, C-terminal domain
      Family: Methylated DNA-protein cysteine methyltransferase, C-terminal domain
O6-alkylguanine-DNA alkyltransferase B 92 174 EF  H-Bb H-Mj L-Bb 
Class: Alpha and beta proteins (a/b)
  Fold: Ribonuclease H-like motif
    Superfamily: Methylated DNA-protein cysteine methyltransferase domain
      Family: Methylated DNA-protein cysteine methyltransferase domain
O6-alkylguanine-DNA alkyltransferase A 6 91 -
Class: Alpha and beta proteins (a/b)
  Fold: Ribonuclease H-like motif
    Superfamily: Methylated DNA-protein cysteine methyltransferase domain
      Family: Methylated DNA-protein cysteine methyltransferase domain
O6-alkylguanine-DNA alkyltransferase B 7 91 -
GO terms
Protein chains: GO type: GO description:
A/B=1-176 C membrane
A/B=1-176 C nucleoplasm
A/B=1-176 C nucleus
A/B=1-176 F DNA binding
A/B=1-176 F DNA-methyltransferase activity
A/B=1-176 F metal ion binding
A/B=1-176 F methylated-DNA-[protein]-cysteine S-methyltransferase activity
A/B=1-176 F methyltransferase activity
A/B=1-176 P DNA dealkylation involved in DNA repair
A/B=1-176 P DNA ligation
A/B=1-176 P DNA repair
A/B=1-176 P negative regulation of apoptotic process
A/B=1-176 P positive regulation of double-strand break repair
Sequences
Download file with secondary structure created by Stride  
1t39.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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1t39.pdb2.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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B (protein): 
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