General information
PDB ID 1XPX
Title STRUCTURAL BASIS OF PROSPERO-DNA INTERACTION; IMPLICATIONS FOR TRANSCRIPTION REGULATION IN DEVELOPING CELLS
PDB header TRANSCRIPTION REGULATION/DNA
Date 2004-10-09
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.8
Kind dna
Organism DROSOPHILA MELANOGASTER
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb1xpx.pdb A DC 0
Biounits:
1xpx.pdb1.pdb A DC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
HPD Domain P29617_1547-1700 3.2e-73 1 CL0123 A 1247 1400 C  H-Bb H-Mj L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: Homeodomain-like
      Family: Homeodomain
Homeo-prospero domain of Prospero protein A 1245 1396 C  H-Bb H-Mj L-Bb 
GO terms
Protein chains: GO type: GO description:
A=1541-1703 C apical cortex
A=1541-1703 C basal cortex
A=1541-1703 C cell cortex
A=1541-1703 C nucleus
A=1541-1703 C plasma membrane
A=1541-1703 F DNA binding
A=1541-1703 F DNA-binding transcription factor activity
A=1541-1703 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A=1541-1703 F sequence-specific DNA binding
A=1541-1703 P asymmetric neuroblast division
A=1541-1703 P asymmetric neuroblast division resulting in ganglion mother cell formation
A=1541-1703 P axon development
A=1541-1703 P axon guidance
A=1541-1703 P axonogenesis
A=1541-1703 P axonogenesis involved in innervation
A=1541-1703 P brain development
A=1541-1703 P cell dedifferentiation
A=1541-1703 P cell fate commitment
A=1541-1703 P central nervous system development
A=1541-1703 P dendrite guidance
A=1541-1703 P dendrite morphogenesis
A=1541-1703 P G1 to G0 transition
A=1541-1703 P ganglion mother cell fate determination
A=1541-1703 P glial cell differentiation
A=1541-1703 P male courtship behavior
A=1541-1703 P negative regulation of axonogenesis
A=1541-1703 P negative regulation of cell population proliferation
A=1541-1703 P negative regulation of gene expression
A=1541-1703 P negative regulation of neuroblast proliferation
A=1541-1703 P negative regulation of transcription by RNA polymerase II
A=1541-1703 P nervous system development
A=1541-1703 P neuroblast differentiation
A=1541-1703 P neuroblast proliferation
A=1541-1703 P peripheral nervous system development
A=1541-1703 P positive regulation of gene expression
A=1541-1703 P positive regulation of neuroblast proliferation
A=1541-1703 P positive regulation of transcription by RNA polymerase II
A=1541-1703 P protein localization
A=1541-1703 P R7 cell fate commitment
A=1541-1703 P regulation of DNA-binding transcription factor activity
A=1541-1703 P regulation of gene expression
A=1541-1703 P regulation of neuroblast proliferation
A=1541-1703 P regulation of neuron differentiation
A=1541-1703 P regulation of protein localization to nucleus
A=1541-1703 P regulation of R7 cell differentiation
A=1541-1703 P sensory perception of taste
A=1541-1703 P synapse assembly
Sequences
Download file with secondary structure created by Stride  
1xpx.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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