General information
PDB ID 2A07
Title CRYSTAL STRUCTURE OF FOXP2 BOUND SPECIFICALLY TO DNA.
PDB header TRANSCRIPTION/DNA
Date 2005-06-16
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.9
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2a07.pdb FGHIJK ABCD 0
Biounits:
2a07.pdb1.pdb FGHIJK ABCD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Forkhead Domain O15409_503-584 1.2e-29 1 CL0123 F 503 584 AB  H-Bb H-Mj L-Bb L-Mj 
Forkhead Domain O15409_503-584 6.8e-28 1 CL0123 G 506 584 B  H-Bb L-Bb 
Forkhead Domain O15409_503-584 6.8e-28 1 CL0123 H 506 584 D  H-Bb L-Bb 
Forkhead Domain O15409_503-584 1.4e-29 1 CL0123 I 503 583 CD  H-Bb H-Mj L-Bb L-Mj 
Forkhead Domain O15409_503-584 1.3e-29 1 CL0123 J 503 584 ABCD  H-Bb H-Mj S-Bb L-Bb 
Forkhead Domain O15409_503-584 1.3e-29 1 CL0123 K 503 584 ABCD  H-Bb H-Mj S-Bb L-Bb 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Forkhead DNA-binding domain
Forkhead box protein P2, FOXP2 F 503 584 AB -
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Forkhead DNA-binding domain
Forkhead box protein P2, FOXP2 G 506 584 B -
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Forkhead DNA-binding domain
Forkhead box protein P2, FOXP2 H 506 584 D -
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Forkhead DNA-binding domain
Forkhead box protein P2, FOXP2 I 503 583 CD -
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Forkhead DNA-binding domain
Forkhead box protein P2, FOXP2 J 503 584 ABCD -
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Forkhead DNA-binding domain
Forkhead box protein P2, FOXP2 K 503 584 ABCD -
GO terms
Protein chains: GO type: GO description:
F/G/H/I/J/K=502-594 C nuclear chromatin
F/G/H/I/J/K=502-594 F androgen receptor binding
F/G/H/I/J/K=502-594 F DNA binding
F/G/H/I/J/K=502-594 F DNA-binding transcription factor activity
F/G/H/I/J/K=502-594 F DNA-binding transcription factor activity, RNA polymerase II-specific
F/G/H/I/J/K=502-594 F DNA-binding transcription repressor activity, RNA polymerase II-specific
F/G/H/I/J/K=502-594 F identical protein binding
F/G/H/I/J/K=502-594 F metal ion binding
F/G/H/I/J/K=502-594 F protein homodimerization activity
F/G/H/I/J/K=502-594 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
F/G/H/I/J/K=502-594 F sequence-specific DNA binding
F/G/H/I/J/K=502-594 P camera-type eye development
F/G/H/I/J/K=502-594 P caudate nucleus development
F/G/H/I/J/K=502-594 P cerebellum development
F/G/H/I/J/K=502-594 P cerebral cortex development
F/G/H/I/J/K=502-594 P innate vocalization behavior
F/G/H/I/J/K=502-594 P lung alveolus development
F/G/H/I/J/K=502-594 P negative regulation of transcription, DNA-templated
F/G/H/I/J/K=502-594 P positive regulation of epithelial cell proliferation involved in lung morphogenesis
F/G/H/I/J/K=502-594 P positive regulation of mesenchymal cell proliferation
F/G/H/I/J/K=502-594 P post-embryonic development
F/G/H/I/J/K=502-594 P putamen development
F/G/H/I/J/K=502-594 P response to testosterone
F/G/H/I/J/K=502-594 P righting reflex
F/G/H/I/J/K=502-594 P skeletal muscle tissue development
F/G/H/I/J/K=502-594 P smooth muscle tissue development
F/G/H/I/J/K=502-594 P vocal learning
Sequences
Download file with secondary structure created by Stride  
2a07.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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C (dna): 
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D (dna): 
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F (protein): 
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G (protein): 
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H (protein): 
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I (protein): 
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J (protein): 
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K (protein): 
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