General information
PDB ID 2GO5
Title STRUCTURE OF SIGNAL RECOGNITION PARTICLE RECEPTOR (SR) IN COMPLEX WITH SIGNAL RECOGNITION PARTICLE (SRP) AND RIBOSOME NASCENT CHAIN COMPLEX
PDB header TRANSLATION/RNA
Date 2006-04-12
Experimental method ELECTRON MICROSCOPY
Resolution (A) 7.4
Kind rna
Organism CANIS SP., TRITICUM SP., HOMO SAPIENS, MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
PRIDB
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2go5.pdb BW12546 A9 0
Biounits:
2go5.pdb1.pdb BW12546 A9 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
SRPRB Domain P47758_63-239 1.3e-61 1 CL0023 2 63 239   
SRP_SPB Domain P61010_326-431 1.1e-32 1 CL0123 W 326 431 A   
SRP-alpha_N Family P08240_27-130 2.4e-35 1 CL0431 1 27 130 A   
Ribosomal_L23 Family O81229_28-101 1e-14 1 No_clan 4 71 144   
Ribosomal_L29 Family Q8L805_9-65 4e-20 1 CL0346 5 9 65   
Ribosomal_L31e Family Q5XLD9_18-96 3.9e-41 1 No_clan 6 17 95 9   
SRP19 Family Q5RBR1_17-115 2.2e-29 1 CL0123 B 17 115 A   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a+b)
  Fold: Profilin-like
    Superfamily: SNARE-like
      Family: SRP alpha N-terminal domain-like
Signal recognition particle receptor alpha subunit, N-terminal domain 1 1 129 A -
Class: Alpha and beta proteins (a/b)
  Fold: P-loop containing nucleoside triphosphate hydrolases
    Superfamily: P-loop containing nucleoside triphosphate hydrolases
      Family: G proteins
Signal recognition particle receptor beta-subunit 2 63 269 -
Class: Alpha and beta proteins (a+b)
  Fold: SRP19
    Superfamily: SRP19
      Family: SRP19
SRP19 B 14 118 A -
Class: All alpha proteins
  Fold: Signal peptide-binding domain
    Superfamily: Signal peptide-binding domain
      Family: Signal peptide-binding domain
SRP54M W 326 434 A -
GO terms
Protein chains: GO type: GO description:
1=3-176 C endoplasmic reticulum membrane
1=3-176 C extracellular exosome
1=3-176 C membrane
1=3-176 C signal recognition particle receptor complex
1=3-176 F GTP binding
1=3-176 F GTPase activity
1=3-176 F RNA binding
1=3-176 F signal recognition particle binding
1=3-176 P cotranslational protein targeting to membrane
1=3-176 P IRE1-mediated unfolded protein response
1=3-176 P protein targeting
1=3-176 P protein targeting to ER
1=3-176 P SRP-dependent cotranslational protein targeting to membrane
2=58-269 C cytoplasm
2=58-269 C cytoplasmic microtubule
2=58-269 C endoplasmic reticulum membrane
2=58-269 C integral component of membrane
2=58-269 C membrane
2=58-269 F GTP binding
2=58-269 F ubiquitin protein ligase binding
5=1-124 C cytosolic large ribosomal subunit
5=1-124 F mRNA binding
5=1-124 F structural constituent of ribosome
5=1-124 P maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
5=1-124 P translation
B=14-120 C signal recognition particle, endoplasmic reticulum targeting
B=14-120 F 7S RNA binding
B=14-120 P SRP-dependent cotranslational protein targeting to membrane
W=326-434 C cytosol
W=326-434 C endoplasmic reticulum
W=326-434 C nuclear speck
W=326-434 C nucleus
W=326-434 C signal recognition particle, endoplasmic reticulum targeting
W=326-434 F 7S RNA binding
W=326-434 F drug binding
W=326-434 F endoplasmic reticulum signal peptide binding
W=326-434 F GDP binding
W=326-434 F GTP binding
W=326-434 F GTPase activity
W=326-434 F ribonucleoprotein complex binding
W=326-434 P exocrine pancreas development
W=326-434 P granulocyte differentiation
W=326-434 P neutrophil chemotaxis
W=326-434 P protein targeting to ER
W=326-434 P response to drug
W=326-434 P SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
W=326-434 P SRP-dependent cotranslational protein targeting to membrane, translocation
Sequences
Download file with secondary structure created by Stride  
2go5.pdb1.pdb:   [ download sequences in FASTA format ]
1 (protein): 
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2 (protein): 
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4 (protein): 
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5 (protein): 
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6 (protein): 
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B (protein): 
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W (protein): 
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9 (rna): 
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A (rna): 
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