General information
PDB ID 2IRF
Title CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX.
PDB header GENE REGULATION/DNA
Date 1999-05-30
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.2
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2irf.pdb GHIJKL ABCDEF 0
Biounits:
2irf.pdb1.pdb GH AF 1
2irf.pdb2.pdb IJ BE 1
2irf.pdb3.pdb KL CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
IRF Domain P23906_7-112 5.3e-44 1 CL0123 G 7 112 F  H-Bb H-Mj L-Bb 
IRF Domain P23906_7-112 5.3e-44 1 CL0123 H 207 312 AF  H-Bb H-Mj S-Bb L-Bb L-Mn 
IRF Domain P23906_7-112 5.3e-44 1 CL0123 I 407 512 E  H-Bb H-Mj L-Bb 
IRF Domain P23906_7-112 5.3e-44 1 CL0123 J 607 712 BE  H-Bb H-Mj S-Bb L-Bb L-Mn 
IRF Domain P23906_7-112 5.3e-44 1 CL0123 K 807 912 D  H-Bb H-Mj L-Bb 
IRF Domain P23906_7-112 5.3e-44 1 CL0123 L 2007 2112 CD  H-Bb H-Mj S-Bb L-Bb L-Mn 
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Interferon regulatory factor
Interferon regulatory factor-2, IRF-2 G N/A N/A F  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Interferon regulatory factor
Interferon regulatory factor-2, IRF-2 H N/A N/A AF  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Interferon regulatory factor
Interferon regulatory factor-2, IRF-2 I N/A N/A E  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Interferon regulatory factor
Interferon regulatory factor-2, IRF-2 J N/A N/A BE  H-Bb H-Mj S-Bb L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Interferon regulatory factor
Interferon regulatory factor-2, IRF-2 K N/A N/A D  H-Bb H-Mj L-Bb 
Class: All alpha proteins
  Fold: DNA/RNA-binding 3-helical bundle
    Superfamily: "Winged helix" DNA-binding domain
      Family: Interferon regulatory factor
Interferon regulatory factor-2, IRF-2 L N/A N/A CD  H-Bb H-Mj S-Bb L-Bb 
GO terms
Protein chains: GO type: GO description:
G/H/I/J/K/L=1-113 C cytosol
G/H/I/J/K/L=1-113 C focal adhesion
G/H/I/J/K/L=1-113 C nucleoplasm
G/H/I/J/K/L=1-113 C nucleus
G/H/I/J/K/L=1-113 F DNA binding
G/H/I/J/K/L=1-113 F DNA-binding transcription activator activity, RNA polymerase II-specific
G/H/I/J/K/L=1-113 F DNA-binding transcription factor activity
G/H/I/J/K/L=1-113 F DNA-binding transcription factor activity, RNA polymerase II-specific
G/H/I/J/K/L=1-113 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
G/H/I/J/K/L=1-113 F sequence-specific double-stranded DNA binding
G/H/I/J/K/L=1-113 P cell population proliferation
G/H/I/J/K/L=1-113 P defense response to virus
G/H/I/J/K/L=1-113 P immune system process
G/H/I/J/K/L=1-113 P positive regulation of transcription by RNA polymerase II
G/H/I/J/K/L=1-113 P regulation of transcription, DNA-templated
Sequences
Download file with secondary structure created by Stride  
2irf.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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F (dna): 
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G (protein): 
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H (protein): 
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2irf.pdb2.pdb:   [ download sequences in FASTA format ]
B (dna): 
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E (dna): 
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I (protein): 
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J (protein): 
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2irf.pdb3.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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K (protein): 
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L (protein): 
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