General information
PDB ID 2J0S
Title THE CRYSTAL STRUCTURE OF THE EXON JUNCTION COMPLEX AT 2.2 A RESOLUTION
PDB header HYDROLASE
Date 2006-08-04
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.21
Kind rna
Organism HOMO SAPIENS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
PRIDB
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2j0s.pdb ACDT E 0
Biounits:
2j0s.pdb1.pdb ACDT E 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
DEAD Domain P38919_62-228 2.6e-42 1 CL0023 A 62 228 E   
Helicase_C Domain P38919_263-372 2.4e-31 1 CL0023 A 263 372 E   
RRM_1 Domain Q9Y5S9_75-145 1e-18 1 CL0221 D 75 145   
Btz Domain O15234_169-230 9.6e-10 1 No_clan T 169 217 E   
Mago_nashi Family P61326_5-146 3.6e-78 1 No_clan C 5 146   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a/b)
  Fold: P-loop containing nucleoside triphosphate hydrolases
    Superfamily: P-loop containing nucleoside triphosphate hydrolases
      Family: Tandem AAA-ATPase domain
Probable ATP-dependent RNA helicase DDX48 A 22 243 E -
Class: Alpha and beta proteins (a/b)
  Fold: P-loop containing nucleoside triphosphate hydrolases
    Superfamily: P-loop containing nucleoside triphosphate hydrolases
      Family: Tandem AAA-ATPase domain
Probable ATP-dependent RNA helicase DDX48 A 244 411 E -
Class: Alpha and beta proteins (a+b)
  Fold: Mago nashi protein
    Superfamily: Mago nashi protein
      Family: Mago nashi protein
Mago nashi protein C 4 145 -
Class: Alpha and beta proteins (a+b)
  Fold: Ferredoxin-like
    Superfamily: RNA-binding domain, RBD
      Family: Canonical RBD
RNA-binding protein 8 D 66 154 -
GO terms
Protein chains: GO type: GO description:
A=2-411 C catalytic step 2 spliceosome
A=2-411 C cytoplasm
A=2-411 C cytosol
A=2-411 C dendrite
A=2-411 C exon-exon junction complex
A=2-411 C membrane
A=2-411 C neuronal cell body
A=2-411 C nuclear speck
A=2-411 C nucleolus
A=2-411 C nucleoplasm
A=2-411 C nucleus
A=2-411 C postsynaptic cytosol
A=2-411 C U2-type catalytic step 1 spliceosome
A=2-411 F ATP binding
A=2-411 F mRNA binding
A=2-411 F poly(A) binding
A=2-411 F ribonucleoprotein complex binding
A=2-411 F RNA binding
A=2-411 F RNA helicase activity
A=2-411 F RNA stem-loop binding
A=2-411 F selenocysteine insertion sequence binding
A=2-411 P associative learning
A=2-411 P cellular response to brain-derived neurotrophic factor stimulus
A=2-411 P cellular response to selenite ion
A=2-411 P embryonic cranial skeleton morphogenesis
A=2-411 P exploration behavior
A=2-411 P mRNA 3'-end processing
A=2-411 P mRNA export from nucleus
A=2-411 P mRNA splicing, via spliceosome
A=2-411 P negative regulation of excitatory postsynaptic potential
A=2-411 P negative regulation of selenocysteine incorporation
A=2-411 P negative regulation of selenocysteine insertion sequence binding
A=2-411 P negative regulation of translation
A=2-411 P nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
A=2-411 P positive regulation of translation
A=2-411 P response to organic cyclic compound
A=2-411 P RNA export from nucleus
A=2-411 P rRNA processing
C=1-146 C catalytic step 2 spliceosome
C=1-146 C cytoplasm
C=1-146 C exon-exon junction complex
C=1-146 C nuclear speck
C=1-146 C nucleoplasm
C=1-146 C nucleus
C=1-146 F RNA binding
C=1-146 P mRNA 3'-end processing
C=1-146 P mRNA export from nucleus
C=1-146 P mRNA splicing, via spliceosome
C=1-146 P nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
C=1-146 P regulation of alternative mRNA splicing, via spliceosome
C=1-146 P regulation of translation
C=1-146 P RNA export from nucleus
C=1-146 P RNA splicing
D=66-154 C catalytic step 2 spliceosome
D=66-154 C cytoplasm
D=66-154 C cytosol
D=66-154 C dendrite
D=66-154 C exon-exon junction complex
D=66-154 C neuronal cell body
D=66-154 C nuclear speck
D=66-154 C nucleoplasm
D=66-154 C nucleus
D=66-154 C U2-type catalytic step 1 spliceosome
D=66-154 F mRNA binding
D=66-154 F RNA binding
D=66-154 P mRNA 3'-end processing
D=66-154 P mRNA export from nucleus
D=66-154 P mRNA splicing, via spliceosome
D=66-154 P nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
D=66-154 P regulation of alternative mRNA splicing, via spliceosome
D=66-154 P regulation of translation
D=66-154 P RNA export from nucleus
T=137-286 C cytoplasmic stress granule
T=137-286 C cytosol
T=137-286 C dendrite
T=137-286 C exon-exon junction complex
T=137-286 C nuclear membrane
T=137-286 C nuclear speck
T=137-286 C nucleoplasm
T=137-286 C nucleus
T=137-286 C perinuclear region of cytoplasm
T=137-286 C U2-type catalytic step 1 spliceosome
T=137-286 F enzyme binding
T=137-286 F identical protein binding
T=137-286 F RNA binding
T=137-286 F ubiquitin protein ligase binding
T=137-286 P intracellular mRNA localization
T=137-286 P mRNA 3'-end processing
T=137-286 P mRNA export from nucleus
T=137-286 P mRNA splicing, via spliceosome
T=137-286 P nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
T=137-286 P regulation of translation
T=137-286 P RNA export from nucleus
Sequences
Download file with secondary structure created by Stride  
2j0s.pdb1.pdb:   [ download sequences in FASTA format ]
A (protein): 
Click "SHOW" for view sequence
C (protein): 
Click "SHOW" for view sequence
D (protein): 
Click "SHOW" for view sequence
T (protein): 
Click "SHOW" for view sequence
E (rna): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text