General information
PDB ID 2O4I
Title STRUCTURE OF TREX1 IN COMPLEX WITH DNA
PDB header HYDROLASE/DNA
Date 2006-12-04
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.5
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2o4i.pdb AB CD 0
Biounits:
2o4i.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RNase_H_2 Domain Q91XB0_87-215 0.00085 0 CL0219 A 86 222 C   
RNase_H_2 Domain Q91XB0_87-215 0.00083 0 CL0219 B 86 222 D   
SCOP domains
Classification: Protein: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Class: Alpha and beta proteins (a/b)
  Fold: Ribonuclease H-like motif
    Superfamily: Ribonuclease H-like
      Family: DnaQ-like 3'-5' exonuclease
Three prime repair exonuclease 1, TREX1 A 9 234 C -
Class: Alpha and beta proteins (a/b)
  Fold: Ribonuclease H-like motif
    Superfamily: Ribonuclease H-like
      Family: DnaQ-like 3'-5' exonuclease
Three prime repair exonuclease 1, TREX1 B 9 234 D -
GO terms
Protein chains: GO type: GO description:
A/B=9-245 C cytoplasm
A/B=9-245 C cytosol
A/B=9-245 C endoplasmic reticulum
A/B=9-245 C nuclear replication fork
A/B=9-245 C nucleus
A/B=9-245 C oligosaccharyltransferase complex
A/B=9-245 C protein-DNA complex
A/B=9-245 F 3'-5' exonuclease activity
A/B=9-245 F 3'-5'-exodeoxyribonuclease activity
A/B=9-245 F adenyl deoxyribonucleotide binding
A/B=9-245 F DNA binding
A/B=9-245 F DNA binding, bending
A/B=9-245 F double-stranded DNA binding
A/B=9-245 F exodeoxyribonuclease III activity
A/B=9-245 F identical protein binding
A/B=9-245 F magnesium ion binding
A/B=9-245 F MutLalpha complex binding
A/B=9-245 F MutSalpha complex binding
A/B=9-245 F protein homodimerization activity
A/B=9-245 F single-stranded DNA binding
A/B=9-245 F WW domain binding
A/B=9-245 P activation of immune response
A/B=9-245 P adaptive immune response
A/B=9-245 P apoptotic cell clearance
A/B=9-245 P atrial cardiac muscle tissue development
A/B=9-245 P blood vessel development
A/B=9-245 P CD86 biosynthetic process
A/B=9-245 P cellular response to DNA damage stimulus
A/B=9-245 P cellular response to gamma radiation
A/B=9-245 P cellular response to hydroxyurea
A/B=9-245 P cellular response to interferon-beta
A/B=9-245 P cellular response to organic substance
A/B=9-245 P cellular response to oxidative stress
A/B=9-245 P cellular response to reactive oxygen species
A/B=9-245 P cellular response to type I interferon
A/B=9-245 P cellular response to UV
A/B=9-245 P defense response to virus
A/B=9-245 P detection of DNA damage stimulus involved in DNA damage checkpoint
A/B=9-245 P detection of stimulus involved in cell cycle checkpoint
A/B=9-245 P determination of adult lifespan
A/B=9-245 P DNA catabolic process
A/B=9-245 P DNA duplex unwinding
A/B=9-245 P DNA metabolic process
A/B=9-245 P DNA modification
A/B=9-245 P DNA replication
A/B=9-245 P DNA synthesis involved in UV-damage excision repair
A/B=9-245 P establishment of protein localization
A/B=9-245 P generation of precursor metabolites and energy
A/B=9-245 P heart morphogenesis
A/B=9-245 P heart process
A/B=9-245 P immune complex formation
A/B=9-245 P immune response
A/B=9-245 P immune response in brain or nervous system
A/B=9-245 P immunoglobulin biosynthetic process involved in immune response
A/B=9-245 P inflammatory response
A/B=9-245 P inflammatory response to antigenic stimulus
A/B=9-245 P innate immune response
A/B=9-245 P interferon-alpha production
A/B=9-245 P kidney development
A/B=9-245 P lymphoid progenitor cell differentiation
A/B=9-245 P macrophage activation involved in immune response
A/B=9-245 P negative regulation of type I interferon-mediated signaling pathway
A/B=9-245 P organ or tissue specific immune response
A/B=9-245 P protein stabilization
A/B=9-245 P regulation of catalytic activity
A/B=9-245 P regulation of cellular metabolic process
A/B=9-245 P regulation of cellular respiration
A/B=9-245 P regulation of fatty acid metabolic process
A/B=9-245 P regulation of gene expression
A/B=9-245 P regulation of glycolytic process
A/B=9-245 P regulation of immunoglobulin production
A/B=9-245 P regulation of inflammatory response
A/B=9-245 P regulation of innate immune response
A/B=9-245 P regulation of lipid biosynthetic process
A/B=9-245 P regulation of lysosome organization
A/B=9-245 P regulation of protein complex stability
A/B=9-245 P regulation of T cell activation
A/B=9-245 P regulation of tumor necrosis factor production
A/B=9-245 P regulation of type I interferon production
A/B=9-245 P response to UV
A/B=9-245 P signal transduction involved in DNA damage checkpoint
A/B=9-245 P T cell antigen processing and presentation
A/B=9-245 P transposition, RNA-mediated
A/B=9-245 P type I interferon signaling pathway
Sequences
Download file with secondary structure created by Stride  
2o4i.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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