General information
PDB ID 2XCT
Title THE TWINNED 3.35A STRUCTURE OF S. AUREUS GYRASE COMPLEX WITH CIPROFLOXACIN AND DNA
PDB header ISOMERASE/DNA/ANTIBIOTIC
Date 2010-04-25
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.35
Kind dna
Organism STAPHYLOCOCCUS AUREUS, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb2xct.pdb BDSU EFGHVWXY 0
Biounits:
2xct.pdb1.pdb BD EFGH 1
2xct.pdb2.pdb SU VWXY 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
DNA_topoisoIV Family Q99XG5_33-474 3.1e-156 1 No_clan B 1033 1474 EH  H-Bb H-Mj L-Bb L-Mj L-Mn 
DNA_gyraseB_C Family P66937_580-634 6.5e-27 1 No_clan B 544 634   
Toprim Family P66937_430-542 8.5e-17 1 CL0413 B 430 542 H  L-Bb 
DNA_topoisoIV Family Q99XG5_33-474 3.1e-156 1 No_clan D 1033 1474 FG  H-Bb S-Bb S-Mj S-Mn 
DNA_gyraseB_C Family P66937_580-634 1.2e-25 1 No_clan D 544 634 G  H-Bb 
Toprim Family P66937_430-542 8.5e-17 1 CL0413 D 430 542 F  L-Mn 
DNA_topoisoIV Family Q99XG5_33-474 3.1e-156 1 No_clan S 1032 1473 VY  H-Bb S-Bb S-Mj S-Mn L-Bb 
DNA_gyraseB_C Family P66937_580-634 1.3e-24 1 No_clan S 543 634 X  H-Bb 
Toprim Family P66937_430-542 8.4e-17 1 CL0413 S 430 542 WXY  H-Bb L-Bb L-Mn 
DNA_topoisoIV Family Q99XG5_33-474 3.1e-156 1 No_clan U 1033 1474 WX  H-Bb S-Bb S-Mj S-Mn L-Bb 
DNA_gyraseB_C Family P66937_580-634 1.2e-25 1 No_clan U 544 634 Y  H-Bb 
Toprim Family P66937_430-542 8.4e-17 1 CL0413 U 430 542 VXY  H-Bb L-Bb L-Mn 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
B/D/S/U=2-491 C chromosome
B/D/S/U=2-491 C cytoplasm
B/D/S/U=2-491 F ATP binding
B/D/S/U=2-491 F DNA binding
B/D/S/U=2-491 F DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
B/D/S/U=2-491 P DNA topological change
B/D/S/U=2-491 P DNA-dependent DNA replication
B/D/S/U=2-491 P response to antibiotic
B/D/S/U=410-543, B/D/S/U=580-644 C chromosome
B/D/S/U=410-543, B/D/S/U=580-644 C cytoplasm
B/D/S/U=410-543, B/D/S/U=580-644 F ATP binding
B/D/S/U=410-543, B/D/S/U=580-644 F DNA binding
B/D/S/U=410-543, B/D/S/U=580-644 F DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
B/D/S/U=410-543, B/D/S/U=580-644 F metal ion binding
B/D/S/U=410-543, B/D/S/U=580-644 P DNA topological change
B/D/S/U=410-543, B/D/S/U=580-644 P DNA-dependent DNA replication
Sequences
Download file with secondary structure created by Stride  
2xct.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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G (dna): 
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H (dna): 
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B (protein): 
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D (protein): 
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2xct.pdb2.pdb:   [ download sequences in FASTA format ]
V (dna): 
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W (dna): 
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X (dna): 
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Y (dna): 
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S (protein): 
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U (protein): 
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