General information
PDB ID 3CBB
Title CRYSTAL STRUCTURE OF HEPATOCYTE NUCLEAR FACTOR 4ALPHA IN COMPLEX WITH DNA: DIABETES GENE PRODUCT
PDB header TRANSCRIPTION/DNA
Date 2008-02-21
Experimental method X-RAY DIFFRACTION
Resolution (A) 2
Kind dna
Organism HOMO SAPIENS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3cbb.pdb AB CD 0
Biounits:
3cbb.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-C4 Domain P41235_58-127 1.6e-31 1 CL0167 A 49 118 CD  H-Bb H-Mj S-Bb L-Bb 
zf-C4 Domain P41235_58-127 1.7e-31 1 CL0167 B 49 118 CD  H-Bb H-Mj S-Bb L-Bb L-Mj 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B=58-135 C cytoplasm
A/B=58-135 C nuclear chromatin
A/B=58-135 C nucleoplasm
A/B=58-135 C nucleus
A/B=58-135 F chromatin binding
A/B=58-135 F DNA binding
A/B=58-135 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=58-135 F DNA-binding transcription factor activity
A/B=58-135 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=58-135 F fatty acid binding
A/B=58-135 F protein homodimerization activity
A/B=58-135 F RNA polymerase II activating transcription factor binding
A/B=58-135 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=58-135 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/B=58-135 F sequence-specific double-stranded DNA binding
A/B=58-135 F signaling receptor binding
A/B=58-135 F transcription regulatory region sequence-specific DNA binding
A/B=58-135 F zinc ion binding
A/B=58-135 P anatomical structure development
A/B=58-135 P blood coagulation
A/B=58-135 P cell differentiation
A/B=58-135 P cholesterol homeostasis
A/B=58-135 P glucose homeostasis
A/B=58-135 P hepatocyte differentiation
A/B=58-135 P lipid homeostasis
A/B=58-135 P lipid metabolic process
A/B=58-135 P negative regulation of cell growth
A/B=58-135 P negative regulation of cell population proliferation
A/B=58-135 P negative regulation of transcription, DNA-templated
A/B=58-135 P ornithine metabolic process
A/B=58-135 P phospholipid homeostasis
A/B=58-135 P positive regulation of transcription by RNA polymerase II
A/B=58-135 P positive regulation of transcription, DNA-templated
A/B=58-135 P regulation of circadian rhythm
A/B=58-135 P regulation of gastrulation
A/B=58-135 P regulation of growth hormone receptor signaling pathway
A/B=58-135 P regulation of insulin secretion
A/B=58-135 P regulation of lipid metabolic process
A/B=58-135 P regulation of transcription by RNA polymerase II
A/B=58-135 P response to glucose
A/B=58-135 P rhythmic process
A/B=58-135 P sex differentiation
A/B=58-135 P signal transduction involved in regulation of gene expression
A/B=58-135 P SMAD protein signal transduction
A/B=58-135 P transcription initiation from RNA polymerase II promoter
A/B=58-135 P triglyceride homeostasis
A/B=58-135 P type B pancreatic cell development
A/B=58-135 P xenobiotic metabolic process
Sequences
Download file with secondary structure created by Stride  
3cbb.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
Click "SHOW" for view sequence
D (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text