General information
PDB ID 3CO6
Title CRYSTAL STRUCTURE OF FOXO1 DBD BOUND TO DBE1 DNA
PDB header TRANSCRIPTION/DNA
Date 2008-03-27
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.1
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3co6.pdb C AB 0
Biounits:
3co6.pdb1.pdb C AB 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Forkhead Domain Q12778_160-244 2e-27 1 CL0123 C 160 244 AB  H-Bb H-Mj S-Bb L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
C=151-249 C cytoplasm
C=151-249 C cytosol
C=151-249 C mitochondrion
C=151-249 C nuclear chromatin
C=151-249 C nucleoplasm
C=151-249 C nucleus
C=151-249 F beta-catenin binding
C=151-249 F chromatin binding
C=151-249 F DNA-binding transcription activator activity, RNA polymerase II-specific
C=151-249 F DNA-binding transcription factor activity
C=151-249 F DNA-binding transcription factor activity, RNA polymerase II-specific
C=151-249 F DNA-binding transcription repressor activity, RNA polymerase II-specific
C=151-249 F protein phosphatase 2A binding
C=151-249 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
C=151-249 F sequence-specific DNA binding
C=151-249 F transcription coactivator binding
C=151-249 F transcription factor binding
C=151-249 F ubiquitin protein ligase binding
C=151-249 P apoptotic process
C=151-249 P autophagy
C=151-249 P blood vessel development
C=151-249 P cellular glucose homeostasis
C=151-249 P cellular response to cold
C=151-249 P cellular response to dexamethasone stimulus
C=151-249 P cellular response to DNA damage stimulus
C=151-249 P cellular response to hydrogen peroxide
C=151-249 P cellular response to hyperoxia
C=151-249 P cellular response to insulin stimulus
C=151-249 P cellular response to nitric oxide
C=151-249 P cellular response to oxidative stress
C=151-249 P cellular response to starvation
C=151-249 P cytokine-mediated signaling pathway
C=151-249 P enamel mineralization
C=151-249 P endocrine pancreas development
C=151-249 P energy homeostasis
C=151-249 P fat cell differentiation
C=151-249 P glucose homeostasis
C=151-249 P insulin receptor signaling pathway
C=151-249 P negative regulation of apoptotic process
C=151-249 P negative regulation of canonical Wnt signaling pathway
C=151-249 P negative regulation of cardiac muscle hypertrophy in response to stress
C=151-249 P negative regulation of fat cell differentiation
C=151-249 P negative regulation of stress-activated MAPK cascade
C=151-249 P negative regulation of transcription by RNA polymerase II
C=151-249 P negative regulation of transcription, DNA-templated
C=151-249 P neuronal stem cell population maintenance
C=151-249 P positive regulation of apoptotic process
C=151-249 P positive regulation of autophagy
C=151-249 P positive regulation of gluconeogenesis
C=151-249 P positive regulation of protein catabolic process
C=151-249 P positive regulation of transcription by RNA polymerase II
C=151-249 P positive regulation of transcription, DNA-templated
C=151-249 P protein acetylation
C=151-249 P regulation of neural precursor cell proliferation
C=151-249 P regulation of reactive oxygen species metabolic process
C=151-249 P response to fatty acid
C=151-249 P response to fluoride
C=151-249 P temperature homeostasis
Sequences
Download file with secondary structure created by Stride  
3co6.pdb1.pdb:   [ download sequences in FASTA format ]
A (dna): 
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B (dna): 
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C (protein): 
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