General information
PDB ID 3JSM
Title K65R MUTANT HIV-1 REVERSE TRANSCRIPTASE CROSS-LINKED TO DS-DNA AND COMPLEXED WITH TENOFOVIR-DIPHOSPHATE AS THE INCOMING NUCLEOTIDE SUBSTRATE
PDB header TRANSFERASE/DNA COMPLEX
Date 2009-09-10
Experimental method X-RAY DIFFRACTION
Resolution (A) 3
Kind dna
Organism HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3jsm.pdb AB TP 0
Biounits:
3jsm.pdb1.pdb AB TP 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RVT_connect Domain P03366_917-1018 2.5e-59 1 No_clan A 318 419   
RVT_1 Domain P03366_662-833 1.3e-33 1 CL0027 A 63 234 PT  H-Bb S-Bb S-Mn L-Bb L-Mn 
RNase_H Domain P03366_1035-1153 2.4e-28 1 CL0219 A 436 554 P  H-Bb L-Bb L-Mn 
RVT_thumb Domain P03366_840-903 1.1e-19 1 No_clan A 241 304 TP  H-Bb L-Bb 
RVT_connect Domain P03366_917-1018 1.5e-59 1 No_clan B 318 419 P  H-Bb 
RVT_1 Domain P03366_662-833 5.7e-33 1 CL0027 B 63 243   
RVT_thumb Domain P03366_840-903 1.4e-21 1 No_clan B 241 304   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=600-1157, B=600-1028 C host cell nucleus
A=600-1157, B=600-1028 C host cell plasma membrane
A=600-1157, B=600-1028 C host multivesicular body
A=600-1157, B=600-1028 C viral nucleocapsid
A=600-1157, B=600-1028 C virion membrane
A=600-1157, B=600-1028 F aspartic-type endopeptidase activity
A=600-1157, B=600-1028 F DNA binding
A=600-1157, B=600-1028 F DNA-directed DNA polymerase activity
A=600-1157, B=600-1028 F exoribonuclease H activity
A=600-1157, B=600-1028 F lipid binding
A=600-1157, B=600-1028 F RNA binding
A=600-1157, B=600-1028 F RNA-directed DNA polymerase activity
A=600-1157, B=600-1028 F RNA-DNA hybrid ribonuclease activity
A=600-1157, B=600-1028 F structural molecule activity
A=600-1157, B=600-1028 F zinc ion binding
A=600-1157, B=600-1028 P DNA integration
A=600-1157, B=600-1028 P DNA recombination
A=600-1157, B=600-1028 P establishment of integrated proviral latency
A=600-1157, B=600-1028 P induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
A=600-1157, B=600-1028 P suppression by virus of host gene expression
A=600-1157, B=600-1028 P viral entry into host cell
A=600-1157, B=600-1028 P viral genome integration into host DNA
A=600-1157, B=600-1028 P viral penetration into host nucleus
Sequences
Download file with secondary structure created by Stride  
3jsm.pdb1.pdb:   [ download sequences in FASTA format ]
P (dna): 
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T (dna): 
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A (protein): 
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B (protein): 
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