General information
PDB ID 3RNU
Title STRUCTURAL BASIS OF CYTOSOLIC DNA SENSING BY INNATE IMMUNE RECEPTORS
PDB header TRANSCRIPTION ACTIVATOR/DNA
Date 2011-04-22
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.5
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb3rnu.pdb ABCD KL 0
Biounits:
3rnu.pdb1.pdb ABCD KL 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
HIN Family Q16666_574-740 1.1e-73 1 CL0021 A 574 740 KL  H-Bb S-Bb 
HIN Family Q16666_574-740 1.2e-73 1 CL0021 B 574 740 KL  H-Bb L-Bb 
HIN Family Q16666_574-740 1.1e-73 1 CL0021 C 574 740 K  H-Bb L-Bb 
HIN Family Q16666_574-740 1.1e-73 1 CL0021 D 574 740 L  H-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B/C/D=571-766 C cytosol
A/B/C/D=571-766 C membrane
A/B/C/D=571-766 C nuclear speck
A/B/C/D=571-766 C nucleolus
A/B/C/D=571-766 C nucleoplasm
A/B/C/D=571-766 C nucleus
A/B/C/D=571-766 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A/B/C/D=571-766 F double-stranded DNA binding
A/B/C/D=571-766 F identical protein binding
A/B/C/D=571-766 F RNA binding
A/B/C/D=571-766 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B/C/D=571-766 F transcription factor binding
A/B/C/D=571-766 P activation of cysteine-type endopeptidase activity
A/B/C/D=571-766 P activation of innate immune response
A/B/C/D=571-766 P autophagy
A/B/C/D=571-766 P cellular response to glucose starvation
A/B/C/D=571-766 P cellular response to interferon-beta
A/B/C/D=571-766 P cellular response to ionizing radiation
A/B/C/D=571-766 P defense response to virus
A/B/C/D=571-766 P inflammatory response
A/B/C/D=571-766 P innate immune response
A/B/C/D=571-766 P intrinsic apoptotic signaling pathway by p53 class mediator
A/B/C/D=571-766 P intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
A/B/C/D=571-766 P monocyte differentiation
A/B/C/D=571-766 P myeloid cell differentiation
A/B/C/D=571-766 P negative regulation of cysteine-type endopeptidase activity
A/B/C/D=571-766 P negative regulation of DNA binding
A/B/C/D=571-766 P negative regulation of innate immune response
A/B/C/D=571-766 P negative regulation of transcription by RNA polymerase II
A/B/C/D=571-766 P negative regulation of transcription, DNA-templated
A/B/C/D=571-766 P negative regulation of viral genome replication
A/B/C/D=571-766 P positive regulation of cytokine production
A/B/C/D=571-766 P positive regulation of interleukin-1 beta production
A/B/C/D=571-766 P positive regulation of transcription by RNA polymerase II
A/B/C/D=571-766 P positive regulation of type I interferon production
A/B/C/D=571-766 P regulation of autophagy
A/B/C/D=571-766 P regulation of gene expression, epigenetic
Sequences
Download file with secondary structure created by Stride  
3rnu.pdb1.pdb:   [ download sequences in FASTA format ]
K (dna): 
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L (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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