General information
PDB ID 4B3P
Title STRUCTURES OF HIV-1 RT AND RNA-DNA COMPLEX REVEAL A UNIQUE RT CONFORMATION AND SUBSTRATE INTERFACE
PDB header HYDROLASE/RNA/DNA
Date 2012-07-25
Experimental method X-RAY DIFFRACTION
Resolution (A) 4.84
Kind hybrid
Organism HUMAN IMMUNODEFICIENCY VIRUS 1, SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
PRIDB
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4b3p.pdb AB D R 0
Biounits:
4b3p.pdb1.pdb AB D R 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RVT_connect Domain P04585_905-1006 5.2e-59 1 No_clan A 318 419   
RNase_H Domain P04585_1023-1143 2e-22 1 CL0219 A 436 556 D   
RVT_1 Domain P04585_662-821 1.5e-20 1 CL0027 A 55 234 D   
RVT_thumb Domain P04585_828-891 5.4e-20 1 No_clan A 242 304 D   
RVT_connect Domain P04585_905-1006 3.4e-59 1 No_clan B 318 419   
RVT_1 Domain P04585_650-821 1.8e-31 1 CL0027 B 63 255   
RVT_thumb Domain P04585_828-891 5.3e-23 1 No_clan B 241 304   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=588-1145, B=588-1027 C host cell nucleus
A=588-1145, B=588-1027 C host cell plasma membrane
A=588-1145, B=588-1027 C host multivesicular body
A=588-1145, B=588-1027 C viral nucleocapsid
A=588-1145, B=588-1027 C virion membrane
A=588-1145, B=588-1027 F aspartic-type endopeptidase activity
A=588-1145, B=588-1027 F DNA binding
A=588-1145, B=588-1027 F DNA-directed DNA polymerase activity
A=588-1145, B=588-1027 F exoribonuclease H activity
A=588-1145, B=588-1027 F identical protein binding
A=588-1145, B=588-1027 F integrase activity
A=588-1145, B=588-1027 F lipid binding
A=588-1145, B=588-1027 F peptidase activity
A=588-1145, B=588-1027 F RNA binding
A=588-1145, B=588-1027 F RNA-directed DNA polymerase activity
A=588-1145, B=588-1027 F RNA-DNA hybrid ribonuclease activity
A=588-1145, B=588-1027 F structural molecule activity
A=588-1145, B=588-1027 F zinc ion binding
A=588-1145, B=588-1027 P DNA recombination
A=588-1145, B=588-1027 P establishment of integrated proviral latency
A=588-1145, B=588-1027 P fusion of virus membrane with host plasma membrane
A=588-1145, B=588-1027 P induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
A=588-1145, B=588-1027 P nuclear transport
A=588-1145, B=588-1027 P RNA-dependent DNA biosynthetic process
A=588-1145, B=588-1027 P suppression by virus of host gene expression
A=588-1145, B=588-1027 P uncoating of virus
A=588-1145, B=588-1027 P viral genome integration into host DNA
A=588-1145, B=588-1027 P viral genome packaging
A=588-1145, B=588-1027 P viral life cycle
A=588-1145, B=588-1027 P viral penetration into host nucleus
A=588-1145, B=588-1027 P virion assembly
Sequences
Download file with secondary structure created by Stride  
4b3p.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
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A (protein): 
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B (protein): 
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R (rna): 
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