General information
PDB ID 4CN5
Title CRYSTAL STRUCTURE OF THE HUMAN RETINOID X RECEPTOR DNA- BINDING DOMAIN BOUND TO THE HUMAN NR1D1 RESPONSE ELEMENT
PDB header TRANSCRIPTION/DNA
Date 2014-01-21
Experimental method X-RAY DIFFRACTION
Resolution (A) 2
Kind dna
Organism HOMO SAPIENS
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CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
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Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4cn5.pdb AB CD 0
Biounits:
4cn5.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
zf-C4 Domain P19793_133-202 1.4e-33 1 CL0167 A 133 202 CD  H-Bb H-Mj S-Bb S-Mj L-Bb 
zf-C4 Domain P19793_133-202 3.3e-30 1 CL0167 B 133 202 CD  H-Bb H-Mj S-Bb L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B=130-212 C mitochondrion
A/B=130-212 C nuclear chromatin
A/B=130-212 C nucleoplasm
A/B=130-212 C nucleus
A/B=130-212 C protein-containing complex
A/B=130-212 C receptor complex
A/B=130-212 C RNA polymerase II transcription regulator complex
A/B=130-212 F chromatin DNA binding
A/B=130-212 F DNA binding domain binding
A/B=130-212 F DNA-binding transcription factor activity
A/B=130-212 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=130-212 F double-stranded DNA binding
A/B=130-212 F enzyme binding
A/B=130-212 F identical protein binding
A/B=130-212 F LBD domain binding
A/B=130-212 F nuclear receptor activity
A/B=130-212 F nuclear receptor binding
A/B=130-212 F peptide binding
A/B=130-212 F retinoic acid binding
A/B=130-212 F retinoic acid-responsive element binding
A/B=130-212 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=130-212 F RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
A/B=130-212 F RNA polymerase II transcription regulatory region sequence-specific DNA binding
A/B=130-212 F sequence-specific DNA binding
A/B=130-212 F sequence-specific double-stranded DNA binding
A/B=130-212 F steroid hormone receptor activity
A/B=130-212 F transcription regulatory region sequence-specific DNA binding
A/B=130-212 F vitamin D receptor binding
A/B=130-212 F zinc ion binding
A/B=130-212 P anatomical structure development
A/B=130-212 P bile acid and bile salt transport
A/B=130-212 P camera-type eye development
A/B=130-212 P cardiac muscle cell proliferation
A/B=130-212 P cell differentiation
A/B=130-212 P cholesterol metabolic process
A/B=130-212 P embryo implantation
A/B=130-212 P in utero embryonic development
A/B=130-212 P maternal placenta development
A/B=130-212 P modulation by virus of host process
A/B=130-212 P negative regulation of transcription by RNA polymerase II
A/B=130-212 P peroxisome proliferator activated receptor signaling pathway
A/B=130-212 P positive regulation of transcription by RNA polymerase II
A/B=130-212 P positive regulation of transcription, DNA-templated
A/B=130-212 P positive regulation of translational initiation by iron
A/B=130-212 P regulation of branching involved in prostate gland morphogenesis
A/B=130-212 P regulation of lipid metabolic process
A/B=130-212 P regulation of transcription by RNA polymerase II
A/B=130-212 P response to retinoic acid
A/B=130-212 P retinoic acid receptor signaling pathway
A/B=130-212 P secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
A/B=130-212 P transcription initiation from RNA polymerase II promoter
A/B=130-212 P ventricular cardiac muscle cell differentiation
A/B=130-212 P ventricular cardiac muscle tissue morphogenesis
Sequences
Download file with secondary structure created by Stride  
4cn5.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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