General information
PDB ID 4IG8
Title STRUCTURAL BASIS FOR CYTOSOLIC DOUBLE-STRANDED RNA SURVEILLANCE BY HUMAN OAS1
PDB header TRANSFERASE/RNA
Date 2012-12-16
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.7
Kind rna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
PRIDB
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4ig8.pdb A BC 0
Biounits:
4ig8.pdb1.pdb A BC 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
OAS1_C Domain P00973_163-346 2.7e-87 1 No_clan A 163 346 BC   
NTP_transf_2 Family P00973_37-140 4.4e-08 1 CL0260 A 37 141 BC   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=1-347 C cytoplasm
A=1-347 C cytosol
A=1-347 C endoplasmic reticulum
A=1-347 C extracellular region
A=1-347 C membrane
A=1-347 C mitochondrion
A=1-347 C nucleoplasm
A=1-347 C nucleus
A=1-347 F 2'-5'-oligoadenylate synthetase activity
A=1-347 F ATP binding
A=1-347 F double-stranded RNA binding
A=1-347 F metal ion binding
A=1-347 P cellular response to interferon-alpha
A=1-347 P defense response to virus
A=1-347 P glucose homeostasis
A=1-347 P glucose metabolic process
A=1-347 P interferon-gamma-mediated signaling pathway
A=1-347 P negative regulation of viral genome replication
A=1-347 P protein complex oligomerization
A=1-347 P purine nucleotide biosynthetic process
A=1-347 P regulation of ribonuclease activity
A=1-347 P response to virus
A=1-347 P type I interferon signaling pathway
Sequences
Download file with secondary structure created by Stride  
4ig8.pdb1.pdb:   [ download sequences in FASTA format ]
A (protein): 
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B (rna): 
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C (rna): 
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