General information
PDB ID 4LG0
Title STRUCTURE OF A TERNARY FOXO1-ETS1 DNA COMPLEX
PDB header TRANSCRIPTION/DNA
Date 2013-06-27
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.19
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4lg0.pdb AB CD 0
Biounits:
4lg0.pdb1.pdb AB CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Forkhead Domain Q12778_160-244 1.8e-27 1 CL0123 A 160 244 CD  H-Bb H-Mj S-Bb L-Bb L-Mj 
Ets Domain P14921_336-415 9e-36 1 CL0123 B 336 415 CD  H-Bb H-Mj S-Bb L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=143-270 C cytoplasm
A=143-270 C cytosol
A=143-270 C mitochondrion
A=143-270 C nuclear chromatin
A=143-270 C nucleoplasm
A=143-270 C nucleus
A=143-270 F beta-catenin binding
A=143-270 F chromatin binding
A=143-270 F DNA-binding transcription activator activity, RNA polymerase II-specific
A=143-270 F DNA-binding transcription factor activity
A=143-270 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=143-270 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A=143-270 F protein phosphatase 2A binding
A=143-270 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A=143-270 F sequence-specific DNA binding
A=143-270 F transcription coactivator binding
A=143-270 F transcription factor binding
A=143-270 F ubiquitin protein ligase binding
A=143-270 P apoptotic process
A=143-270 P autophagy
A=143-270 P blood vessel development
A=143-270 P cellular glucose homeostasis
A=143-270 P cellular response to cold
A=143-270 P cellular response to dexamethasone stimulus
A=143-270 P cellular response to DNA damage stimulus
A=143-270 P cellular response to hydrogen peroxide
A=143-270 P cellular response to hyperoxia
A=143-270 P cellular response to insulin stimulus
A=143-270 P cellular response to nitric oxide
A=143-270 P cellular response to oxidative stress
A=143-270 P cellular response to starvation
A=143-270 P cytokine-mediated signaling pathway
A=143-270 P enamel mineralization
A=143-270 P endocrine pancreas development
A=143-270 P energy homeostasis
A=143-270 P fat cell differentiation
A=143-270 P glucose homeostasis
A=143-270 P insulin receptor signaling pathway
A=143-270 P negative regulation of apoptotic process
A=143-270 P negative regulation of canonical Wnt signaling pathway
A=143-270 P negative regulation of cardiac muscle hypertrophy in response to stress
A=143-270 P negative regulation of fat cell differentiation
A=143-270 P negative regulation of stress-activated MAPK cascade
A=143-270 P negative regulation of transcription by RNA polymerase II
A=143-270 P negative regulation of transcription, DNA-templated
A=143-270 P neuronal stem cell population maintenance
A=143-270 P positive regulation of apoptotic process
A=143-270 P positive regulation of autophagy
A=143-270 P positive regulation of gluconeogenesis
A=143-270 P positive regulation of protein catabolic process
A=143-270 P positive regulation of transcription by RNA polymerase II
A=143-270 P positive regulation of transcription, DNA-templated
A=143-270 P protein acetylation
A=143-270 P regulation of neural precursor cell proliferation
A=143-270 P regulation of reactive oxygen species metabolic process
A=143-270 P response to fatty acid
A=143-270 P response to fluoride
A=143-270 P temperature homeostasis
B=331-440 C cytoplasm
B=331-440 C host cell nucleus
B=331-440 C nuclear chromatin
B=331-440 C nucleoplasm
B=331-440 C nucleus
B=331-440 C transcription regulator complex
B=331-440 F DNA binding
B=331-440 F DNA-binding transcription activator activity, RNA polymerase II-specific
B=331-440 F DNA-binding transcription factor activity
B=331-440 F DNA-binding transcription factor activity, RNA polymerase II-specific
B=331-440 F histone acetyltransferase binding
B=331-440 F identical protein binding
B=331-440 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
B=331-440 F transcription factor binding
B=331-440 P angiogenesis involved in wound healing
B=331-440 P cell differentiation
B=331-440 P cell motility
B=331-440 P cellular response to hydrogen peroxide
B=331-440 P estrous cycle
B=331-440 P female pregnancy
B=331-440 P hypothalamus development
B=331-440 P immune response
B=331-440 P negative regulation of cell cycle
B=331-440 P negative regulation of cell population proliferation
B=331-440 P negative regulation of inflammatory response
B=331-440 P pituitary gland development
B=331-440 P PML body organization
B=331-440 P positive regulation of angiogenesis
B=331-440 P positive regulation of blood vessel endothelial cell migration
B=331-440 P positive regulation of cell population proliferation
B=331-440 P positive regulation of cellular component movement
B=331-440 P positive regulation of endothelial cell migration
B=331-440 P positive regulation of erythrocyte differentiation
B=331-440 P positive regulation of gene expression
B=331-440 P positive regulation of inflammatory response
B=331-440 P positive regulation of leukocyte adhesion to vascular endothelial cell
B=331-440 P positive regulation of pri-miRNA transcription by RNA polymerase II
B=331-440 P positive regulation of transcription by RNA polymerase II
B=331-440 P positive regulation of transcription, DNA-templated
B=331-440 P regulation of angiogenesis
B=331-440 P regulation of apoptotic process
B=331-440 P regulation of extracellular matrix disassembly
B=331-440 P regulation of transcription by RNA polymerase II
B=331-440 P response to antibiotic
B=331-440 P response to estradiol
B=331-440 P response to hypoxia
B=331-440 P response to interleukin-1
B=331-440 P response to laminar fluid shear stress
B=331-440 P response to mechanical stimulus
B=331-440 P transcription by RNA polymerase II
Sequences
Download file with secondary structure created by Stride  
4lg0.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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