General information
PDB ID 4XRM
Title HOMODIMER OF TALE TYPE HOMEOBOX TRANSCRIPTION FACTOR MEIS1 COMPLEXES WITH SPECIFIC DNA
PDB header TRANSCRIPTION
Date 2015-01-21
Experimental method X-RAY DIFFRACTION
Resolution (A) 1.6
Kind dna
Organism SYNTHETIC CONSTRUCT, HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4xrm.pdb AB ML 0
Biounits:
4xrm.pdb1.pdb AB ML 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Homeobox_KN Family O14770_294-333 9.5e-22 1 CL0123 A 290 329 LM  H-Bb H-Mj L-Bb 
Homeobox_KN Family O14770_294-333 1.2e-21 1 CL0123 B 290 329 LM  H-Bb H-Mj L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B=281-342 C nuclear chromatin
A/B=281-342 C perinuclear region of cytoplasm
A/B=281-342 F DNA binding
A/B=281-342 F DNA-binding transcription activator activity, RNA polymerase II-specific
A/B=281-342 F DNA-binding transcription factor activity, RNA polymerase II-specific
A/B=281-342 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A/B=281-342 F sequence-specific DNA binding
A/B=281-342 F sequence-specific double-stranded DNA binding
A/B=281-342 F transcription factor binding
A/B=281-342 P animal organ morphogenesis
A/B=281-342 P brain development
A/B=281-342 P embryonic pattern specification
A/B=281-342 P eye development
A/B=281-342 P negative regulation of myeloid cell differentiation
A/B=281-342 P negative regulation of transcription by RNA polymerase II
A/B=281-342 P pancreas development
A/B=281-342 P positive regulation of cardiac muscle myoblast proliferation
A/B=281-342 P positive regulation of cell population proliferation
A/B=281-342 P positive regulation of mitotic cell cycle
A/B=281-342 P positive regulation of transcription by RNA polymerase II
A/B=281-342 P response to growth factor
A/B=281-342 P response to mechanical stimulus
A/B=281-342 P visual learning
Sequences
Download file with secondary structure created by Stride  
4xrm.pdb1.pdb:   [ download sequences in FASTA format ]
L (dna): 
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M (dna): 
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A (protein): 
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B (protein): 
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