General information
PDB ID 4YO2
Title STRUCTURE OF E2F8, AN ATYPICAL MEMBER OF E2F FAMILY OF TRANSCRIPTION FACTORS
PDB header TRANSCRIPTION
Date 2015-03-11
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.07
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb4yo2.pdb A CD 0
Biounits:
4yo2.pdb1.pdb A CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
E2F_TDP Domain A0AVK6_114-182 4e-23 1 CL0123 A 114 182 CD  H-Bb H-Mj S-Bb L-Bb L-Mj 
E2F_TDP Domain A0AVK6_262-341 1.1e-17 1 CL0123 A 262 339 CD  H-Bb H-Mj L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=110-341 C cytosol
A=110-341 C nuclear chromatin
A=110-341 C nucleolus
A=110-341 C nucleoplasm
A=110-341 C nucleus
A=110-341 C RNA polymerase II transcription regulator complex
A=110-341 F cis-regulatory region sequence-specific DNA binding
A=110-341 F DNA binding
A=110-341 F DNA-binding transcription factor activity
A=110-341 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=110-341 F DNA-binding transcription repressor activity
A=110-341 F DNA-binding transcription repressor activity, RNA polymerase II-specific
A=110-341 F identical protein binding
A=110-341 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A=110-341 F sequence-specific DNA binding
A=110-341 F sequence-specific double-stranded DNA binding
A=110-341 F transcription factor binding
A=110-341 P cell cycle comprising mitosis without cytokinesis
A=110-341 P cell population proliferation
A=110-341 P chorionic trophoblast cell differentiation
A=110-341 P DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
A=110-341 P hepatocyte differentiation
A=110-341 P negative regulation of cytokinesis
A=110-341 P negative regulation of transcription by RNA polymerase II
A=110-341 P placenta development
A=110-341 P positive regulation of DNA endoreduplication
A=110-341 P positive regulation of transcription by RNA polymerase II
A=110-341 P regulation of cell cycle
A=110-341 P sprouting angiogenesis
A=110-341 P trophoblast giant cell differentiation
Sequences
Download file with secondary structure created by Stride  
4yo2.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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