General information
PDB ID 5BK4
Title CRYO-EM STRUCTURE OF MCM2-7 DOUBLE HEXAMER ON DSDNA
PDB header HYDROLASE/DNA
Date 2017-09-12
Experimental method ELECTRON MICROSCOPY
Resolution (A) 3.9
Kind dna
Organism SACCHAROMYCES CEREVISIAE
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5bk4.pdb 234567ABCDEF SO 0
Biounits:
5bk4.pdb1.pdb 234567ABCDEF SO 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
MCM Domain P29469_480-703 2.5e-102 1 CL0023 2 480 703   
MCM_OB Domain P29469_305-434 1.1e-36 1 CL0021 2 305 434   
MCM_lid Domain P29469_761-845 5e-26 1 CL0671 2 761 845   
MCM_N Domain P29469_208-299 1e-11 1 No_clan 2 208 299   
MCM Domain P24279_346-569 6.1e-98 1 CL0023 3 346 569   
MCM_OB Domain P24279_166-302 1.3e-32 1 CL0021 3 166 302   
MCM_lid Domain P24279_654-737 3.4e-24 1 CL0671 3 654 737   
MCM_N Domain P24279_25-159 1.9e-07 1 No_clan 3 25 215   
MCM Domain P30665_505-728 1e-101 1 CL0023 4 505 728 O   
MCM_OB Domain P30665_313-443 1.7e-36 1 CL0021 4 313 443   
MCM_lid Domain P30665_745-833 3.5e-27 1 CL0671 4 745 833   
MCM_N Domain P30665_191-307 4.8e-16 1 No_clan 4 191 307   
MCM Domain P29496_353-576 1.2e-104 1 CL0023 5 353 576 O   
MCM_OB Domain P29496_146-302 4.3e-37 1 CL0021 5 146 302   
MCM_lid Domain P29496_597-688 1.1e-27 1 CL0671 5 597 688   
MCM_N Domain P29496_28-110 1.7e-16 1 No_clan 5 28 141   
MCM Domain P53091_512-735 1.4e-103 1 CL0023 6 512 735 S   
MCM_OB Domain P53091_275-405 1.7e-40 1 CL0021 6 275 405   
MCM_lid Domain P53091_749-835 9e-27 1 CL0671 6 749 835   
MCM_N Domain P53091_112-269 3.1e-22 1 No_clan 6 112 269   
MCM Domain P38132_397-620 7.7e-103 1 CL0023 7 397 620   
MCM_OB Domain P38132_226-359 4.5e-32 1 CL0021 7 226 359   
MCM_lid Domain P38132_636-724 3e-22 1 CL0671 7 636 724   
MCM_N Domain P38132_18-206 1.5e-14 1 No_clan 7 18 206   
MCM Domain P29469_480-703 2.5e-102 1 CL0023 A 480 703   
MCM_OB Domain P29469_305-434 1.1e-36 1 CL0021 A 305 434 O   
MCM_lid Domain P29469_761-845 5e-26 1 CL0671 A 761 845   
MCM_N Domain P29469_208-299 1e-11 1 No_clan A 208 299   
MCM Domain P24279_346-569 6.1e-98 1 CL0023 B 346 569 S   
MCM_OB Domain P24279_166-302 1.3e-32 1 CL0021 B 166 302   
MCM_lid Domain P24279_654-737 3.4e-24 1 CL0671 B 654 737   
MCM_N Domain P24279_25-159 1.9e-07 1 No_clan B 25 215   
MCM Domain P30665_505-728 1e-101 1 CL0023 C 505 728 S   
MCM_OB Domain P30665_313-443 1.7e-36 1 CL0021 C 313 443   
MCM_lid Domain P30665_745-833 3.5e-27 1 CL0671 C 745 833   
MCM_N Domain P30665_191-307 4.8e-16 1 No_clan C 191 307   
MCM Domain P29496_353-576 1.2e-104 1 CL0023 D 353 576 S   
MCM_OB Domain P29496_146-302 4.3e-37 1 CL0021 D 146 302   
MCM_lid Domain P29496_597-688 1.1e-27 1 CL0671 D 597 688   
MCM_N Domain P29496_28-110 1.7e-16 1 No_clan D 28 141   
MCM Domain P53091_512-735 1.4e-103 1 CL0023 E 512 735 O   
MCM_OB Domain P53091_275-405 1.7e-40 1 CL0021 E 275 405   
MCM_lid Domain P53091_749-835 9e-27 1 CL0671 E 749 835   
MCM_N Domain P53091_112-269 3.1e-22 1 No_clan E 112 269   
MCM Domain P38132_397-620 7.7e-103 1 CL0023 F 397 620 S   
MCM_OB Domain P38132_226-359 4.5e-32 1 CL0021 F 226 359   
MCM_lid Domain P38132_636-724 3e-22 1 CL0671 F 636 724   
MCM_N Domain P38132_18-206 1.5e-14 1 No_clan F 18 206   
Gly-zipper_YMGG Domain 0.00065 0 CL0500 O 1 60
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
2/A=1-868 C CMG complex
2/A=1-868 C cytoplasm
2/A=1-868 C DNA replication preinitiation complex
2/A=1-868 C MCM complex
2/A=1-868 C nuclear pre-replicative complex
2/A=1-868 C nucleoplasm
2/A=1-868 C nucleus
2/A=1-868 C replication fork protection complex
2/A=1-868 F ATP binding
2/A=1-868 F chromatin binding
2/A=1-868 F DNA helicase activity
2/A=1-868 F DNA replication origin binding
2/A=1-868 F metal ion binding
2/A=1-868 F single-stranded DNA binding
2/A=1-868 P cellular response to DNA damage stimulus
2/A=1-868 P DNA strand elongation involved in DNA replication
2/A=1-868 P DNA unwinding involved in DNA replication
2/A=1-868 P double-strand break repair via break-induced replication
2/A=1-868 P mitotic DNA replication initiation
2/A=1-868 P negative regulation of DNA helicase activity
2/A=1-868 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
3/B=1-971 C chromosome, telomeric region
3/B=1-971 C CMG complex
3/B=1-971 C cytoplasm
3/B=1-971 C DNA replication preinitiation complex
3/B=1-971 C MCM complex
3/B=1-971 C nuclear pre-replicative complex
3/B=1-971 C nucleoplasm
3/B=1-971 C nucleus
3/B=1-971 C replication fork protection complex
3/B=1-971 F ATP binding
3/B=1-971 F chromatin binding
3/B=1-971 F DNA helicase activity
3/B=1-971 F DNA replication origin binding
3/B=1-971 F MCM complex binding
3/B=1-971 F single-stranded DNA binding
3/B=1-971 P chromatin silencing at telomere
3/B=1-971 P DNA replication initiation
3/B=1-971 P DNA strand elongation involved in DNA replication
3/B=1-971 P double-strand break repair via break-induced replication
3/B=1-971 P mitotic DNA replication initiation
3/B=1-971 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
3/B=1-971 P silent mating-type cassette heterochromatin assembly
4/C=1-933 C CMG complex
4/C=1-933 C cytoplasm
4/C=1-933 C DNA replication preinitiation complex
4/C=1-933 C MCM complex
4/C=1-933 C MCM core complex
4/C=1-933 C nuclear pre-replicative complex
4/C=1-933 C nuclear replication fork
4/C=1-933 C nucleoplasm
4/C=1-933 C nucleus
4/C=1-933 C replication fork protection complex
4/C=1-933 F ATP binding
4/C=1-933 F DNA helicase activity
4/C=1-933 F DNA replication origin binding
4/C=1-933 F single-stranded DNA binding
4/C=1-933 P DNA replication initiation
4/C=1-933 P DNA strand elongation involved in DNA replication
4/C=1-933 P DNA unwinding involved in DNA replication
4/C=1-933 P double-strand break repair via break-induced replication
4/C=1-933 P mitotic DNA replication initiation
4/C=1-933 P nuclear DNA replication
4/C=1-933 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
4/C=1-933 P protein hexamerization
5/D=1-775 C CMG complex
5/D=1-775 C cytoplasm
5/D=1-775 C DNA replication preinitiation complex
5/D=1-775 C MCM complex
5/D=1-775 C nuclear chromosome, telomeric region
5/D=1-775 C nuclear pre-replicative complex
5/D=1-775 C nucleoplasm
5/D=1-775 C nucleus
5/D=1-775 C replication fork protection complex
5/D=1-775 F ATP binding
5/D=1-775 F chromatin binding
5/D=1-775 F DNA helicase activity
5/D=1-775 F DNA replication origin binding
5/D=1-775 F single-stranded DNA binding
5/D=1-775 P chromatin silencing at telomere
5/D=1-775 P DNA replication initiation
5/D=1-775 P double-strand break repair via break-induced replication
5/D=1-775 P heterochromatin assembly
5/D=1-775 P negative regulation of chromatin silencing at telomere
5/D=1-775 P nuclear DNA replication
5/D=1-775 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
5/D=1-775 P regulation of DNA-dependent DNA replication initiation
6/E=1-1017 C CMG complex
6/E=1-1017 C cytoplasm
6/E=1-1017 C DNA replication preinitiation complex
6/E=1-1017 C MCM complex
6/E=1-1017 C MCM core complex
6/E=1-1017 C nuclear pre-replicative complex
6/E=1-1017 C nucleoplasm
6/E=1-1017 C nucleus
6/E=1-1017 C replication fork protection complex
6/E=1-1017 F ATP binding
6/E=1-1017 F DNA replication origin binding
6/E=1-1017 F single-stranded DNA binding
6/E=1-1017 F single-stranded DNA helicase activity
6/E=1-1017 P DNA replication initiation
6/E=1-1017 P DNA strand elongation involved in DNA replication
6/E=1-1017 P DNA unwinding involved in DNA replication
6/E=1-1017 P double-strand break repair via break-induced replication
6/E=1-1017 P mitotic DNA replication
6/E=1-1017 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
7/F=1-845 C chromosome, telomeric region
7/F=1-845 C CMG complex
7/F=1-845 C cytoplasm
7/F=1-845 C DNA replication preinitiation complex
7/F=1-845 C MCM complex
7/F=1-845 C MCM core complex
7/F=1-845 C nuclear pre-replicative complex
7/F=1-845 C nucleoplasm
7/F=1-845 C nucleus
7/F=1-845 C replication fork protection complex
7/F=1-845 F ATP binding
7/F=1-845 F chromatin binding
7/F=1-845 F DNA replication origin binding
7/F=1-845 F MCM complex binding
7/F=1-845 F single-stranded DNA binding
7/F=1-845 F single-stranded DNA helicase activity
7/F=1-845 P chromatin silencing at telomere
7/F=1-845 P DNA replication initiation
7/F=1-845 P DNA strand elongation involved in DNA replication
7/F=1-845 P DNA unwinding involved in DNA replication
7/F=1-845 P double-strand break repair via break-induced replication
7/F=1-845 P nuclear DNA replication
7/F=1-845 P pre-replicative complex assembly involved in nuclear cell cycle DNA replication
7/F=1-845 P silent mating-type cassette heterochromatin assembly
Sequences
Download file with secondary structure created by Stride  
5bk4.pdb1.pdb:   [ download sequences in FASTA format ]
O (dna): 
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S (dna): 
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2 (protein): 
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3 (protein): 
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4 (protein): 
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5 (protein): 
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6 (protein): 
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7 (protein): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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