General information
PDB ID 5E5A
Title CRYSTAL STRUCTURE OF THE CHROMATIN-TETHERING DOMAIN OF HUMAN CYTOMEGALOVIRUS IE1 PROTEIN BOUND TO THE NUCLEOSOME CORE PARTICLE
PDB header PROTEIN BINDING/VIRAL PROTEIN/DNA
Date 2015-10-08
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.81
Kind dna
Organism HOMO SAPIENS, XENOPUS LAEVIS, HUMAN HERPESVIRUS 5 STRAIN TOWNE
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5e5a.pdb ABCDEFGHK IJ 0
Biounits:
5e5a.pdb1.pdb ABCDEFGHK IJ 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain P84233_37-132 4e-46 1 CL0012 A 37 131 IJ  H-Bb H-Mj S-Bb L-Bb L-Mn 
CENP-T_C Domain P62799_26-99 4.4e-08 1 CL0012 B 26 98 IJ  H-Bb S-Bb L-Bb 
Histone Domain P06897_19-91 8.9e-16 1 CL0012 C 14 90 IJ  H-Bb S-Bb L-Bb 
Histone Domain P02281_28-102 8.1e-23 1 CL0012 D 24 98 IJ  H-Bb H-Mj S-Bb L-Bb L-Mn 
Histone Domain P84233_37-132 8.2e-46 1 CL0012 E 38 131 IJ  H-Bb H-Mj S-Bb L-Bb L-Mn 
CENP-T_C Domain P62799_18-99 5.2e-08 1 CL0012 F 23 98 IJ  H-Bb H-Mj S-Bb L-Bb 
Histone Domain P06897_19-91 8.9e-16 1 CL0012 G 14 90 IJ  H-Bb S-Bb L-Bb 
Histone Domain P02281_33-102 6.9e-22 1 CL0012 H 28 98 IJ  H-Bb S-Bb L-Bb 
Histone_H2A_C Family P06897_92-120 3e-17 1 No_clan C 91 118   
Histone_H2A_C Family P06897_92-120 3e-17 1 No_clan G 91 118   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/E=1-136 C nucleoplasm
A/E=1-136 C nucleosome
A/E=1-136 F DNA binding
A/E=1-136 F protein heterodimerization activity
B/F=1-103 C host cell nucleus
B/F=1-103 C nucleosome
B/F=1-103 C nucleus
B/F=1-103 F DNA binding
B/F=1-103 F protein heterodimerization activity
B/F=1-103 P DNA-templated transcription, initiation
C/G=1-130 C nucleosome
C/G=1-130 C nucleus
C/G=1-130 F DNA binding
C/G=1-130 F protein heterodimerization activity
D/H=5-126 C nucleosome
D/H=5-126 C nucleus
D/H=5-126 F DNA binding
D/H=5-126 F protein heterodimerization activity
K=476-491 C host cell nucleus
K=476-491 P DNA-templated viral transcription
K=476-491 P modulation by virus of host G1/S transition checkpoint
K=476-491 P regulation of viral process
K=476-491 P suppression by virus of host type I interferon-mediated signaling pathway
Sequences
Download file with secondary structure created by Stride  
5e5a.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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C (protein): 
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D (protein): 
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E (protein): 
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F (protein): 
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G (protein): 
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H (protein): 
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K (protein): 
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