General information
PDB ID 5EG0
Title HOXB13-MEIS1 HETERODIMER BOUND TO DNA
PDB header TRANSCRIPTION
Date 2015-10-26
Experimental method X-RAY DIFFRACTION
Resolution (A) 3.1
Kind dna
Organism HOMO SAPIENS, SYNTHETIC CONSTRUCT
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5eg0.pdb AB DE 0
Biounits:
5eg0.pdb1.pdb AB DE 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Homeodomain Domain Q92826_217-273 3.9e-19 1 CL0123 B 217 273 DE  H-Bb H-Mj L-Bb L-Mn 
Homeobox_KN Family O14770_294-333 8.1e-22 1 CL0123 A 290 329 DE  H-Bb H-Mj L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=284-338 C nuclear chromatin
A=284-338 C perinuclear region of cytoplasm
A=284-338 F DNA binding
A=284-338 F DNA-binding transcription activator activity, RNA polymerase II-specific
A=284-338 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=284-338 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A=284-338 F sequence-specific DNA binding
A=284-338 F sequence-specific double-stranded DNA binding
A=284-338 F transcription factor binding
A=284-338 P animal organ morphogenesis
A=284-338 P brain development
A=284-338 P embryonic pattern specification
A=284-338 P eye development
A=284-338 P negative regulation of myeloid cell differentiation
A=284-338 P negative regulation of transcription by RNA polymerase II
A=284-338 P pancreas development
A=284-338 P positive regulation of cardiac muscle myoblast proliferation
A=284-338 P positive regulation of cell population proliferation
A=284-338 P positive regulation of mitotic cell cycle
A=284-338 P positive regulation of transcription by RNA polymerase II
A=284-338 P response to growth factor
A=284-338 P response to mechanical stimulus
A=284-338 P visual learning
B=217-277 C nuclear chromatin
B=217-277 C nucleoplasm
B=217-277 C transcription regulator complex
B=217-277 F DNA-binding transcription factor activity, RNA polymerase II-specific
B=217-277 F DNA-binding transcription repressor activity, RNA polymerase II-specific
B=217-277 F methyl-CpG binding
B=217-277 F sequence-specific DNA binding
B=217-277 F sequence-specific double-stranded DNA binding
B=217-277 P angiogenesis
B=217-277 P epidermis development
B=217-277 P epithelial cell maturation involved in prostate gland development
B=217-277 P negative regulation of transcription by RNA polymerase II
B=217-277 P prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
B=217-277 P regulation of growth
B=217-277 P response to testosterone
B=217-277 P response to wounding
Sequences
Download file with secondary structure created by Stride  
5eg0.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
Click "SHOW" for view sequence
E (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text