General information
PDB ID 5HQ2
Title STRUCTURAL MODEL OF SET8 HISTONE H4 LYS20 METHYLTRANSFERASE BOUND TO NUCLEOSOME CORE PARTICLE
PDB header TRANSFERASE/DNA
Date 2016-01-21
Experimental method X-RAY DIFFRACTION
Resolution (A) 4.5
Kind dna
Organism XENOPUS LAEVIS, SYNTHETIC CONSTRUCT, HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5hq2.pdb ABGHKM IJ 0
Biounits:
5hq2.pdb1.pdb ABGHKM IJ 2
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Histone Domain P84233_37-132 4e-46 1 CL0012 A 37 131 IJ   
CENP-T_C Domain P62799_26-99 4.2e-08 1 CL0012 B 26 98 J   
Histone Domain P06897_19-91 1e-15 1 CL0012 G 15 90 IJ   
Histone Domain P02281_33-102 7.2e-22 1 CL0012 H 28 98 I   
Histone_H2A_C Family P06897_92-120 3.9e-18 1 No_clan G 91 119   
SET Family Q9NQR1_268-378 1.3e-18 1 No_clan M 227 337 J   
RCC1 Repeat P21827_412-463 3.9e-08 1 CL0186 K 410 461   
RCC1_2 Repeat P21827_276-305 4e-08 1 CL0186 K 274 303   
RCC1 Repeat P21827_102-180 7.4e-08 1 CL0186 K 102 180   
RCC1 Repeat P21827_47-99 2.9e-06 1 CL0186 K 47 99   
RCC1 Repeat P21827_348-409 1.1e-05 1 CL0186 K 346 407   
RCC1 Repeat P21827_47-99 0.00025 1 CL0186 K 183 236   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=2-136 C nucleoplasm
A=2-136 C nucleosome
A=2-136 F DNA binding
A=2-136 F protein heterodimerization activity
B=2-103 C host cell nucleus
B=2-103 C nucleosome
B=2-103 C nucleus
B=2-103 F DNA binding
B=2-103 F protein heterodimerization activity
B=2-103 P DNA-templated transcription, initiation
G=2-130 C nucleosome
G=2-130 C nucleus
G=2-130 F DNA binding
G=2-130 F protein heterodimerization activity
H=5-126 C nucleosome
H=5-126 C nucleus
H=5-126 F DNA binding
H=5-126 F protein heterodimerization activity
K=2-482 C cytoplasm
K=2-482 C nuclear chromatin
K=2-482 C nucleus
K=2-482 F chromatin binding
K=2-482 F Ran guanyl-nucleotide exchange factor activity
K=2-482 P cell cycle
K=2-482 P cell division
K=2-482 P nucleus organization
K=2-482 P poly(A)+ mRNA export from nucleus
K=2-482 P protein import into nucleus
K=2-482 P Ran protein signal transduction
K=2-482 P regulation of mitotic spindle assembly
K=2-482 P response to pheromone
K=2-482 P ribosomal subunit export from nucleus
K=2-482 P rRNA export from nucleus
M=194-393 C chromosome
M=194-393 C cytosol
M=194-393 C nucleoplasm
M=194-393 F histone methyltransferase activity (H4-K20 specific)
M=194-393 F histone-lysine N-methyltransferase activity
M=194-393 F lysine N-methyltransferase activity
M=194-393 F p53 binding
M=194-393 F protein-lysine N-methyltransferase activity
M=194-393 F transcription corepressor activity
M=194-393 P cell cycle
M=194-393 P cell division
M=194-393 P negative regulation of transcription by RNA polymerase II
M=194-393 P negative regulation of transcription, DNA-templated
M=194-393 P peptidyl-lysine monomethylation
M=194-393 P regulation of DNA damage response, signal transduction by p53 class mediator
M=194-393 P regulation of signal transduction by p53 class mediator
Sequences
Download file with secondary structure created by Stride  
5hq2.pdb1.pdb:   [ download sequences in FASTA format ]
I (dna): 
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J (dna): 
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A (protein): 
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B (protein): 
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G (protein): 
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H (protein): 
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K (protein): 
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M (protein): 
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