General information
PDB ID 5ITR
Title CRYSTAL STRUCTURE OF HUMAN NEIL1(P2G) BOUND TO DUPLEX DNA CONTAINING THF
PDB header DNA BINDING PROTEIN/DNA
Date 2016-03-17
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.46
Kind dna
Organism HOMO SAPIENS, UNIDENTIFIED
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5itr.pdb ABC DEF 0
Biounits:
5itr.pdb1.pdb A D 1
5itr.pdb2.pdb B E 1
5itr.pdb3.pdb C F 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Neil1-DNA_bind Domain Q96FI4_252-290 7.9e-25 1 No_clan A 252 290 D  L-Bb L-Mj 
Fapy_DNA_glyco Domain Q96FI4_2-123 1.1e-14 1 No_clan A 2 123 D  S-Bb L-Bb L-Mj L-Mn 
H2TH Domain Q96FI4_144-223 4.8e-09 1 CL0303 A 134 248 D  H-Bb L-Bb 
Neil1-DNA_bind Domain Q96FI4_252-290 1.7e-24 1 No_clan B 243 290 E  S-Bb L-Bb 
Fapy_DNA_glyco Domain Q96FI4_2-123 1e-14 1 No_clan B 2 123 E  S-Bb L-Bb L-Mj L-Mn 
H2TH Domain Q96FI4_144-217 1.1e-08 1 CL0303 B 134 256 E  H-Bb L-Bb 
Neil1-DNA_bind Domain Q96FI4_252-290 2.3e-21 1 No_clan C 252 290 F  S-Bb 
Fapy_DNA_glyco Domain Q96FI4_2-123 8.5e-15 1 No_clan C 2 123 F  S-Bb L-Bb L-Mj L-Mn 
H2TH Domain Q96FI4_141-197 1.3e-08 1 CL0303 C 134 255 F  H-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/B/C=1-390 C chromosome
A/B/C=1-390 C cytoplasm
A/B/C=1-390 C microtubule organizing center
A/B/C=1-390 C nucleoplasm
A/B/C=1-390 C nucleus
A/B/C=1-390 F class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A/B/C=1-390 F damaged DNA binding
A/B/C=1-390 F DNA N-glycosylase activity
A/B/C=1-390 F DNA-(apurinic or apyrimidinic site) endonuclease activity
A/B/C=1-390 F hydrolase activity, acting on glycosyl bonds
A/B/C=1-390 F protein C-terminus binding
A/B/C=1-390 F zinc ion binding
A/B/C=1-390 P base-excision repair
A/B/C=1-390 P depyrimidination
A/B/C=1-390 P negative regulation of nuclease activity
A/B/C=1-390 P nucleotide-excision repair
A/B/C=1-390 P response to oxidative stress
Sequences
Download file with secondary structure created by Stride  
5itr.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
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A (protein): 
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5itr.pdb2.pdb:   [ download sequences in FASTA format ]
E (dna): 
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B (protein): 
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5itr.pdb3.pdb:   [ download sequences in FASTA format ]
F (dna): 
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C (protein): 
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