General information
PDB ID 5XZB
Title MOUSE CGAS BOUND TO THE INHIBITOR RU365
PDB header IMMUNE SYSTEM/INHIBITOR
Date 2017-07-12
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.13
Kind dna
Organism MUS MUSCULUS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
 PDIdb 
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5xzb.pdb A EF 0
Biounits:
5xzb.pdb1.pdb A EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
Mab-21 Family Q8C6L5_200-495 2.9e-79 1 No_clan A 200 495 EF  H-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=149-505 C cytosol
A=149-505 C nucleus
A=149-505 C plasma membrane
A=149-505 C site of double-strand break
A=149-505 F ATP binding
A=149-505 F chromatin binding
A=149-505 F cyclic-GMP-AMP synthase activity
A=149-505 F DNA binding
A=149-505 F double-stranded DNA binding
A=149-505 F GTP binding
A=149-505 F metal ion binding
A=149-505 F phosphatidylinositol-4,5-bisphosphate binding
A=149-505 P activation of innate immune response
A=149-505 P cellular response to DNA damage stimulus
A=149-505 P cellular response to exogenous dsRNA
A=149-505 P defense response to virus
A=149-505 P determination of adult lifespan
A=149-505 P DNA repair
A=149-505 P innate immune response
A=149-505 P negative regulation of double-strand break repair via homologous recombination
A=149-505 P paracrine signaling
A=149-505 P positive regulation of cAMP-mediated signaling
A=149-505 P positive regulation of cellular senescence
A=149-505 P positive regulation of cGMP-mediated signaling
A=149-505 P positive regulation of defense response to virus by host
A=149-505 P positive regulation of type I interferon production
A=149-505 P regulation of immune response
A=149-505 P regulation of immunoglobulin production
A=149-505 P regulation of T cell activation
A=149-505 P regulation of type I interferon production
Sequences
Download file with secondary structure created by Stride  
5xzb.pdb1.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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A (protein): 
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