General information
PDB ID 5ZMC
Title STRUCTURAL BASIS FOR REACTIVATION OF -146C>T MUTANT TERT PROMOTER BY COOPERATIVE BINDING OF P52 AND ETS1/2
PDB header TRANSCRIPTION/DNA
Date 2018-04-02
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.99
Kind dna
Organism HOMO SAPIENS
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb5zmc.pdb BA CD 0
Biounits:
5zmc.pdb1.pdb BA CD 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RHD_dimer Domain Q00653_229-327 5.2e-40 1 CL0159 A 229 328   
Ets Domain P14921_336-415 9e-36 1 CL0123 B 336 415 CD  H-Bb H-Mj L-Bb 
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=35-329 C Bcl3/NF-kappaB2 complex
A=35-329 C cytoplasm
A=35-329 C cytosol
A=35-329 C host cell nucleus
A=35-329 C nuclear chromatin
A=35-329 C nucleoplasm
A=35-329 C nucleus
A=35-329 F DNA-binding transcription activator activity, RNA polymerase II-specific
A=35-329 F DNA-binding transcription factor activity
A=35-329 F DNA-binding transcription factor activity, RNA polymerase II-specific
A=35-329 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
A=35-329 F sequence-specific double-stranded DNA binding
A=35-329 P aging
A=35-329 P extracellular matrix organization
A=35-329 P follicular dendritic cell differentiation
A=35-329 P germinal center formation
A=35-329 P NIK/NF-kappaB signaling
A=35-329 P positive regulation of NF-kappaB transcription factor activity
A=35-329 P positive regulation of transcription by RNA polymerase II
A=35-329 P positive regulation of type I interferon production
A=35-329 P regulation of transcription, DNA-templated
A=35-329 P response to cytokine
A=35-329 P response to lipopolysaccharide
A=35-329 P rhythmic process
A=35-329 P spleen development
B=331-441 C cytoplasm
B=331-441 C host cell nucleus
B=331-441 C nuclear chromatin
B=331-441 C nucleoplasm
B=331-441 C nucleus
B=331-441 C transcription regulator complex
B=331-441 F DNA binding
B=331-441 F DNA-binding transcription activator activity, RNA polymerase II-specific
B=331-441 F DNA-binding transcription factor activity
B=331-441 F DNA-binding transcription factor activity, RNA polymerase II-specific
B=331-441 F histone acetyltransferase binding
B=331-441 F identical protein binding
B=331-441 F RNA polymerase II cis-regulatory region sequence-specific DNA binding
B=331-441 F transcription factor binding
B=331-441 P angiogenesis involved in wound healing
B=331-441 P cell differentiation
B=331-441 P cell motility
B=331-441 P cellular response to hydrogen peroxide
B=331-441 P estrous cycle
B=331-441 P female pregnancy
B=331-441 P hypothalamus development
B=331-441 P immune response
B=331-441 P negative regulation of cell cycle
B=331-441 P negative regulation of cell population proliferation
B=331-441 P negative regulation of inflammatory response
B=331-441 P pituitary gland development
B=331-441 P PML body organization
B=331-441 P positive regulation of angiogenesis
B=331-441 P positive regulation of blood vessel endothelial cell migration
B=331-441 P positive regulation of cell population proliferation
B=331-441 P positive regulation of cellular component movement
B=331-441 P positive regulation of endothelial cell migration
B=331-441 P positive regulation of erythrocyte differentiation
B=331-441 P positive regulation of gene expression
B=331-441 P positive regulation of inflammatory response
B=331-441 P positive regulation of leukocyte adhesion to vascular endothelial cell
B=331-441 P positive regulation of pri-miRNA transcription by RNA polymerase II
B=331-441 P positive regulation of transcription by RNA polymerase II
B=331-441 P positive regulation of transcription, DNA-templated
B=331-441 P regulation of angiogenesis
B=331-441 P regulation of apoptotic process
B=331-441 P regulation of extracellular matrix disassembly
B=331-441 P regulation of transcription by RNA polymerase II
B=331-441 P response to antibiotic
B=331-441 P response to estradiol
B=331-441 P response to hypoxia
B=331-441 P response to interleukin-1
B=331-441 P response to laminar fluid shear stress
B=331-441 P response to mechanical stimulus
B=331-441 P transcription by RNA polymerase II
Sequences
Download file with secondary structure created by Stride  
5zmc.pdb1.pdb:   [ download sequences in FASTA format ]
C (dna): 
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D (dna): 
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A (protein): 
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B (protein): 
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