General information
PDB ID 6AN8
Title STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 8.0
PDB header TRANSFERASE/DNA
Date 2017-08-12
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.6
Kind dna
Organism SYNTHETIC CONSTRUCT
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PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6an8.pdb ABCD TPEF 0
Biounits:
6an8.pdb1.pdb AB TP 1
6an8.pdb2.pdb CD EF 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RVT_connect Domain P03366_917-1018 2.5e-59 1 No_clan A 318 419 PT  H-Bb S-Bb L-Bb 
RVT_1 Domain P03366_662-833 3.8e-34 1 CL0027 A 63 234 PT  H-Bb S-Bb L-Bb L-Mn 
RNase_H Domain P03366_1035-1153 3.5e-28 1 CL0219 A 436 553 PT  H-Bb H-Mn L-Bb 
RVT_thumb Domain P03366_840-903 2.2e-21 1 No_clan A 241 304 PT  H-Bb L-Bb 
RVT_connect Domain P03366_917-1018 1.5e-59 1 No_clan B 318 419   
RVT_1 Domain P03366_662-833 2e-32 1 CL0027 B 63 258   
RVT_thumb Domain P03366_840-903 1.4e-21 1 No_clan B 241 304   
RVT_connect Domain P03366_917-1018 2.5e-59 1 No_clan C 318 419 EF  S-Bb L-Bb 
RVT_1 Domain P03366_662-833 3.8e-34 1 CL0027 C 63 234 FE  H-Bb S-Bb S-Mn L-Bb L-Mn 
RNase_H Domain P03366_1035-1153 3.5e-28 1 CL0219 C 436 553 FE  H-Bb L-Bb L-Mn 
RVT_thumb Domain P03366_840-903 2.2e-21 1 No_clan C 241 304 EF  H-Bb L-Bb 
RVT_connect Domain P03366_917-1018 3e-52 1 No_clan D 318 419 F  H-Bb 
RVT_1 Domain P03366_662-833 2.2e-35 1 CL0027 D 63 259   
RVT_thumb Domain P03366_840-903 1.4e-21 1 No_clan D 241 304   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A/C=600-1153, B/D=600-1027 C host cell nucleus
A/C=600-1153, B/D=600-1027 C host cell plasma membrane
A/C=600-1153, B/D=600-1027 C host multivesicular body
A/C=600-1153, B/D=600-1027 C viral nucleocapsid
A/C=600-1153, B/D=600-1027 C virion membrane
A/C=600-1153, B/D=600-1027 F aspartic-type endopeptidase activity
A/C=600-1153, B/D=600-1027 F DNA binding
A/C=600-1153, B/D=600-1027 F DNA-directed DNA polymerase activity
A/C=600-1153, B/D=600-1027 F exoribonuclease H activity
A/C=600-1153, B/D=600-1027 F lipid binding
A/C=600-1153, B/D=600-1027 F RNA binding
A/C=600-1153, B/D=600-1027 F RNA-directed DNA polymerase activity
A/C=600-1153, B/D=600-1027 F RNA-DNA hybrid ribonuclease activity
A/C=600-1153, B/D=600-1027 F structural molecule activity
A/C=600-1153, B/D=600-1027 F zinc ion binding
A/C=600-1153, B/D=600-1027 P DNA integration
A/C=600-1153, B/D=600-1027 P DNA recombination
A/C=600-1153, B/D=600-1027 P establishment of integrated proviral latency
A/C=600-1153, B/D=600-1027 P induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
A/C=600-1153, B/D=600-1027 P suppression by virus of host gene expression
A/C=600-1153, B/D=600-1027 P viral entry into host cell
A/C=600-1153, B/D=600-1027 P viral genome integration into host DNA
A/C=600-1153, B/D=600-1027 P viral penetration into host nucleus
Sequences
Download file with secondary structure created by Stride  
6an8.pdb1.pdb:   [ download sequences in FASTA format ]
P (dna): 
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T (dna): 
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A (protein): 
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B (protein): 
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6an8.pdb2.pdb:   [ download sequences in FASTA format ]
E (dna): 
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F (dna): 
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C (protein): 
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D (protein): 
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