General information
PDB ID 6BSH
Title STRUCTURE OF HIV-1 RT COMPLEXED WITH RNA/DNA HYBRID IN THE RNA HYDROLYSIS MODE
PDB header VIRAL PROTEIN/DNA/RNA/INHIBITOR
Date 2017-12-03
Experimental method X-RAY DIFFRACTION
Resolution (A) 2.65
Kind hybrid
Organism HUMAN IMMUNODEFICIENCY VIRUS 1, HOMO SAPIENS
Download
complex
View in
Jmol
Quick Links
PDB PDBe MMDB Jena OCA
CATH PDBsum HSSP PDBePISA UniProt
ProteopediA BIPA
PRIDB
Composition of PDB entry and biounits
File: Protein chains: DNA chains: RNA chains: No. of models: Action:
PDB entry:
pdb6bsh.pdb AB D R 0
Biounits:
6bsh.pdb1.pdb AB D R 1
Pfam domains
Name: Type: Domain: E-value: Significance: Clan: Prot. chain: Start res.: End res.: Nuc. chains: Int. mode: Action:
RVT_connect Domain P04585_905-1006 5.6e-59 1 No_clan A 318 419 DR   
RVT_1 Domain P04585_662-821 1.4e-31 1 CL0027 A 51 234 RD   
RNase_H Domain P04585_1023-1143 1.4e-28 1 CL0219 A 436 557 DR   
RVT_thumb Domain P04585_828-891 8.1e-23 1 No_clan A 241 304 DR   
RVT_connect Domain P04585_905-1006 7.1e-52 1 No_clan B 318 419 DR   
RVT_1 Domain P04585_650-821 7.4e-32 1 CL0027 B 63 245   
RVT_thumb Domain P04585_828-891 5.3e-23 1 No_clan B 241 304 R   
SCOP domains
No SCOP domains
GO terms
Protein chains: GO type: GO description:
A=588-1144, B=588-1027 C host cell nucleus
A=588-1144, B=588-1027 C host cell plasma membrane
A=588-1144, B=588-1027 C host multivesicular body
A=588-1144, B=588-1027 C viral nucleocapsid
A=588-1144, B=588-1027 C virion membrane
A=588-1144, B=588-1027 F aspartic-type endopeptidase activity
A=588-1144, B=588-1027 F DNA binding
A=588-1144, B=588-1027 F DNA-directed DNA polymerase activity
A=588-1144, B=588-1027 F exoribonuclease H activity
A=588-1144, B=588-1027 F identical protein binding
A=588-1144, B=588-1027 F integrase activity
A=588-1144, B=588-1027 F lipid binding
A=588-1144, B=588-1027 F peptidase activity
A=588-1144, B=588-1027 F RNA binding
A=588-1144, B=588-1027 F RNA-directed DNA polymerase activity
A=588-1144, B=588-1027 F RNA-DNA hybrid ribonuclease activity
A=588-1144, B=588-1027 F structural molecule activity
A=588-1144, B=588-1027 F zinc ion binding
A=588-1144, B=588-1027 P DNA recombination
A=588-1144, B=588-1027 P establishment of integrated proviral latency
A=588-1144, B=588-1027 P fusion of virus membrane with host plasma membrane
A=588-1144, B=588-1027 P induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
A=588-1144, B=588-1027 P nuclear transport
A=588-1144, B=588-1027 P RNA-dependent DNA biosynthetic process
A=588-1144, B=588-1027 P suppression by virus of host gene expression
A=588-1144, B=588-1027 P uncoating of virus
A=588-1144, B=588-1027 P viral genome integration into host DNA
A=588-1144, B=588-1027 P viral genome packaging
A=588-1144, B=588-1027 P viral life cycle
A=588-1144, B=588-1027 P viral penetration into host nucleus
A=588-1144, B=588-1027 P virion assembly
A=600-1156 C host cell nucleus
A=600-1156 C host cell plasma membrane
A=600-1156 C host multivesicular body
A=600-1156 C viral nucleocapsid
A=600-1156 C virion membrane
A=600-1156 F aspartic-type endopeptidase activity
A=600-1156 F DNA binding
A=600-1156 F DNA-directed DNA polymerase activity
A=600-1156 F exoribonuclease H activity
A=600-1156 F lipid binding
A=600-1156 F RNA binding
A=600-1156 F RNA-directed DNA polymerase activity
A=600-1156 F RNA-DNA hybrid ribonuclease activity
A=600-1156 F structural molecule activity
A=600-1156 F zinc ion binding
A=600-1156 P DNA integration
A=600-1156 P DNA recombination
A=600-1156 P establishment of integrated proviral latency
A=600-1156 P induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process
A=600-1156 P suppression by virus of host gene expression
A=600-1156 P viral entry into host cell
A=600-1156 P viral genome integration into host DNA
A=600-1156 P viral penetration into host nucleus
Sequences
Download file with secondary structure created by Stride  
6bsh.pdb1.pdb:   [ download sequences in FASTA format ]
D (dna): 
Click "SHOW" for view sequence
A (protein): 
Click "SHOW" for view sequence
B (protein): 
Click "SHOW" for view sequence
R (rna): 
Click "SHOW" for view sequence
© NPIDB team 2003 - 2021

text